Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   STMM20_RS03200 Genome accession   NZ_CP065485
Coordinates   609428..610072 (+) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MM20     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 604428..615072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STMM20_RS03180 (STMM20_03175) stkP/pknB 604802..606673 (+) 1872 WP_347103624.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  STMM20_RS03185 - 607311..607478 (+) 168 WP_014608530.1 potassium channel family protein -
  STMM20_RS03190 (STMM20_03185) liaF 607733..608431 (+) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  STMM20_RS03195 (STMM20_03190) - 608428..609438 (+) 1011 WP_011226288.1 sensor histidine kinase -
  STMM20_RS03200 (STMM20_03195) vraR 609428..610072 (+) 645 WP_002951384.1 response regulator transcription factor Regulator
  STMM20_RS03215 (STMM20_03210) rimM 610744..611262 (+) 519 WP_011226286.1 ribosome maturation factor RimM -
  STMM20_RS03220 (STMM20_03215) trmD 611252..611971 (+) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  STMM20_RS03225 (STMM20_03220) - 611973..612971 (+) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=448215 STMM20_RS03200 WP_002951384.1 609428..610072(+) (vraR) [Streptococcus thermophilus strain MM20]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=448215 STMM20_RS03200 WP_002951384.1 609428..610072(+) (vraR) [Streptococcus thermophilus strain MM20]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379