Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ST90728_RS08100 Genome accession   NZ_CP065479
Coordinates   1566851..1568218 (-) Length   455 a.a.
NCBI ID   WP_084829837.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90728     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1561851..1573218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90728_RS08070 (ST90728_08065) - 1562267..1562509 (-) 243 WP_347113968.1 Blp family class II bacteriocin -
  ST90728_RS08075 - 1562760..1563161 (-) 402 WP_011226490.1 hypothetical protein -
  ST90728_RS08080 (ST90728_08070) - 1564129..1564335 (-) 207 WP_084829836.1 bacteriocin class II family protein -
  ST90728_RS08085 (ST90728_08075) comE/blpR 1564586..1565317 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  ST90728_RS08090 comD/blpH 1565821..1566657 (+) 837 WP_232085771.1 ATP-binding protein Regulator
  ST90728_RS08095 (ST90728_08085) - 1566675..1566836 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST90728_RS08100 (ST90728_08090) comB 1566851..1568218 (-) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator
  ST90728_RS08105 (ST90728_08095) - 1568234..1570387 (-) 2154 Protein_1544 peptide cleavage/export ABC transporter -
  ST90728_RS08110 (ST90728_08100) - 1571401..1573146 (-) 1746 WP_002948877.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50399.10 Da        Isoelectric Point: 4.7492

>NTDB_id=447618 ST90728_RS08100 WP_084829837.1 1566851..1568218(-) (comB) [Streptococcus thermophilus strain 90728]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQITDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLESRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=447618 ST90728_RS08100 WP_084829837.1 1566851..1568218(-) (comB) [Streptococcus thermophilus strain 90728]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTACCGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAAGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.246

99.121

0.389
  comB Streptococcus pneumoniae D39

39.246

99.121

0.389
  comB Streptococcus pneumoniae R6

39.246

99.121

0.389
  comB Streptococcus pneumoniae TIGR4

38.581

99.121

0.382
  comB Streptococcus mitis SK321

37.916

99.121

0.376
  comB Streptococcus mitis NCTC 12261

37.916

99.121

0.376