Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ST90728_RS08085 Genome accession   NZ_CP065479
Coordinates   1564586..1565317 (+) Length   243 a.a.
NCBI ID   WP_002948869.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90728     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1559586..1570317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90728_RS08065 (ST90728_08060) - 1560731..1562121 (+) 1391 Protein_1536 IS3-like element ISSth1b family transposase -
  ST90728_RS08070 (ST90728_08065) - 1562267..1562509 (-) 243 WP_347113968.1 Blp family class II bacteriocin -
  ST90728_RS08075 - 1562760..1563161 (-) 402 WP_011226490.1 hypothetical protein -
  ST90728_RS08080 (ST90728_08070) - 1564129..1564335 (-) 207 WP_084829836.1 bacteriocin class II family protein -
  ST90728_RS08085 (ST90728_08075) comE/blpR 1564586..1565317 (+) 732 WP_002948869.1 LytTR family DNA-binding domain-containing protein Regulator
  ST90728_RS08090 comD/blpH 1565821..1566657 (+) 837 WP_232085771.1 ATP-binding protein Regulator
  ST90728_RS08095 (ST90728_08085) - 1566675..1566836 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST90728_RS08100 (ST90728_08090) comB 1566851..1568218 (-) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27803.11 Da        Isoelectric Point: 6.9136

>NTDB_id=447616 ST90728_RS08085 WP_002948869.1 1564586..1565317(+) (comE/blpR) [Streptococcus thermophilus strain 90728]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=447616 ST90728_RS08085 WP_002948869.1 1564586..1565317(+) (comE/blpR) [Streptococcus thermophilus strain 90728]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362