Detailed information NTG0447577

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ST90728_RS03510
• Genome accession: NZ_CP065479
• Coordinates: 653168..655321 (-)
• Length: 717 a.a.
• NCBI ID: WP_024404830.1
• Uniprot ID: A0ABV2EUK0
• Organism: Streptococcus thermophilus strain 90728
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 648168..660321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST90728_RS03480	-	648465..648860 (-)	396	WP_232085807.1	hypothetical protein	-
ST90728_RS03485 (ST90728_03490)	-	649059..649400 (+)	342	WP_024404826.1	LytTR family DNA-binding domain-containing protein	-
ST90728_RS03490 (ST90728_03495)	comE/blpR	649402..650142 (+)	741	WP_347114465.1	response regulator transcription factor	Regulator
ST90728_RS03495 (ST90728_03500)	-	650153..651493 (+)	1341	WP_347114466.1	GHKL domain-containing protein	-
ST90728_RS03500 (ST90728_03505)	-	651541..651696 (-)	156	WP_096811960.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
ST90728_RS03505 (ST90728_03510)	comB	651795..653156 (-)	1362	WP_096811961.1	bacteriocin secretion accessory protein	Regulator
ST90728_RS03510 (ST90728_03515)	comA/nlmT	653168..655321 (-)	2154	WP_024404830.1	peptide cleavage/export ABC transporter	Regulator
ST90728_RS03515 (ST90728_03520)	-	655619..655876 (+)	258	WP_039671027.1	Blp family class II bacteriocin	-
ST90728_RS03520 (ST90728_03525)	-	655893..656087 (+)	195	WP_039671026.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
ST90728_RS03525 (ST90728_03530)	-	656690..658041 (+)	1352	WP_096811962.1	IS3 family transposase	-
ST90728_RS03530 (ST90728_03535)	-	658462..659493 (+)	1032	WP_065973046.1	thioredoxin fold domain-containing protein	-
ST90728_RS03535 (ST90728_03540)	-	659497..660192 (+)	696	WP_065973047.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80548.46 Da
• Isoelectric Point: 7.1814

>NTDB_id=447577 ST90728_RS03510 WP_024404830.1 653168..655321(-) (comA/nlmT) [Streptococcus thermophilus strain 90728]
MTAYKRTFVPQIDARDCGVAALASIAKFYGSDYSLAHLRELAKTNKEGTTALGIVKAAKEMGFETRAIQADMSLFDMDDV
PYPFIVHVNKEGKLQHYYVVYHNKKDHLIIGDPDPTVKVTKMTKERFASEWTGVAIFLAPEPSYKPHKDKKNGLMSFLPL
IFRQRALIFYIVLASLLVTLINIGGSYYLQGILDEYIPNQMKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILTIVGGVLLVQNTNLFLLSLISVPIYII
IIFAFMKPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKSFKLSKYSILQTTLKQGAQL
ILNIVILWFGAQLVMNGHISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVESEFSNSQTLTDSQFL
TGDIRFEDLSYKYGFGRDTLSDINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYKGRITINNNDLKLIDKKTLRQHI
NYLPQQAYIFSGSILENLTLGANQLISQEDIIRACEIAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKKVIDNLMAMADKTIIFVAHRLSISERTNQVIVLDQGKVIETGSHHELMTKQGFYHHLFSK

Nucleotide

• Length: 2154 bp

>NTDB_id=447577 ST90728_RS03510 WP_024404830.1 653168..655321(-) (comA/nlmT) [Streptococcus thermophilus strain 90728]
ATGACAGCTTACAAACGAACTTTTGTTCCTCAAATCGATGCCAGAGACTGTGGTGTGGCTGCTTTAGCCTCTATTGCCAA
GTTTTATGGTTCTGATTATTCCCTAGCTCATTTGAGAGAATTGGCCAAAACCAATAAGGAAGGAACGACCGCTCTTGGTA
TCGTCAAAGCAGCCAAGGAGATGGGCTTTGAAACTAGAGCCATCCAGGCTGACATGAGCCTCTTTGATATGGATGACGTT
CCCTATCCCTTCATCGTTCACGTCAATAAAGAAGGCAAACTGCAACACTACTATGTGGTCTATCACAACAAAAAAGACCA
CCTCATCATTGGTGATCCTGACCCTACGGTCAAAGTCACCAAGATGACCAAGGAGCGGTTTGCTTCTGAATGGACAGGCG
TTGCTATCTTTCTGGCTCCAGAACCCAGCTATAAGCCTCACAAAGATAAAAAGAACGGCCTGATGAGCTTTCTCCCTCTT
ATTTTCAGGCAACGTGCGCTTATCTTTTATATCGTCTTGGCTAGCCTTTTGGTGACACTTATCAATATTGGTGGTTCTTA
CTACCTGCAAGGGATTTTGGATGAATACATTCCTAATCAAATGAAGTCAACCTTGGGGATTATCTCCATCGGCCTGATTA
TCACCTACATCCTCCAGCAGATGATGAGTTTCTCACGAGATTACCTTTTGACTGTGCTCAGCCAGCGGCTAAGCATTGAT
GTGATTCTTTCCTATATCCGTCATATCTTTGAACTGCCCATGTCCTTTTTTGCGACACGGCGGACTGGTGAGGTTATCTC
TCGCTTTACAGATGCCAATTCAATCATTGATGCCCTGGCATCGACCATTTTGTCACTCTTCCTTGATGTCTCTATTTTAA
CCATCGTCGGTGGTGTGCTTTTGGTACAAAACACCAACCTCTTCCTGCTCTCCTTGATTTCAGTTCCCATTTACATCATC
ATTATTTTTGCTTTTATGAAGCCGTTTGAGAAGATGAATAACGATGTGATGCAGAGCAATTCCATGGTCAGCTCTGCCAT
TATCGAAGACATCAACGGCATTGAAACCATCAAATCCTTGACCAGTGAAGAAAGCCGCTACCAGAAGATTGATAGCGAGT
TCGTAGATTACCTGGACAAATCCTTCAAACTCAGTAAATACTCTATCCTGCAAACTACCCTTAAACAGGGAGCTCAGCTC
ATTCTAAATATTGTCATCTTGTGGTTTGGGGCTCAGCTAGTCATGAACGGACACATTTCAGTTGGACAACTGATCACCTT
CAACACCCTTCTATCTTATTTTACCAATCCTTTAGAAAATATTATAAACCTCCAAACCAAGCTCCAGTCTGCCAAGGTGG
CTAACAATCGCCTGAATGAAGTCTACCTGGTTGAATCTGAATTCAGTAACAGTCAGACCTTAACAGATTCACAGTTCCTG
ACTGGCGATATTCGCTTTGAAGACCTTTCCTATAAGTACGGTTTCGGACGTGACACCCTATCGGATATCAATCTGACCAT
CAAACAAGGCGATAAGGTCAGTCTAGTGGGAATTAGCGGCTCAGGAAAGACAACCTTGGCCAAGATGATTGTCAATTTCT
TTGAGCCTTACAAGGGTCGAATCACCATCAACAACAATGACCTTAAACTAATTGATAAAAAGACGCTTCGGCAACACATT
AACTACCTCCCACAACAAGCTTATATCTTCAGTGGTTCAATCTTAGAAAACTTGACTTTAGGGGCTAATCAACTGATTAG
TCAGGAAGATATTATCAGAGCTTGTGAGATCGCTGAAATTCGACAAGATATCGAGCAGATGCCTATGGGCTATCAAACAG
AATTGTCTGACGGAGCTGGCTTATCGGGTGGTCAAAAGCAACGGATTGCTTTGGCTAGGGCTCTACTGACTAAAGCCCCT
GTTCTTATTCTTGATGAAGCCACTAGCGGCCTTGATGTGCTAACGGAGAAAAAGGTCATTGATAATTTAATGGCCATGGC
AGACAAGACCATTATCTTTGTCGCACACCGCCTCAGTATTTCTGAGCGAACCAACCAAGTTATCGTTCTTGACCAAGGGA
AGGTCATTGAGACTGGTTCACATCACGAATTGATGACCAAACAAGGTTTCTACCATCATCTATTTAGCAAGTAA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (168-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	73.986	99.721	0.738
comA	Streptococcus mitis NCTC 12261	68.495	99.163	0.679
comA	Streptococcus mitis SK321	67.932	99.163	0.674
comA	Streptococcus pneumoniae Rx1	67.792	99.163	0.672
comA	Streptococcus pneumoniae D39	67.792	99.163	0.672
comA	Streptococcus pneumoniae R6	67.792	99.163	0.672
comA	Streptococcus pneumoniae TIGR4	67.511	99.163	0.669
comA	Streptococcus gordonii str. Challis substr. CH1	65.734	99.721	0.656