Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ST90728_RS03505 Genome accession   NZ_CP065479
Coordinates   651795..653156 (-) Length   453 a.a.
NCBI ID   WP_096811961.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90728     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 646795..658156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90728_RS03480 - 648465..648860 (-) 396 WP_232085807.1 hypothetical protein -
  ST90728_RS03485 (ST90728_03490) - 649059..649400 (+) 342 WP_024404826.1 LytTR family DNA-binding domain-containing protein -
  ST90728_RS03490 (ST90728_03495) comE/blpR 649402..650142 (+) 741 WP_347114465.1 response regulator transcription factor Regulator
  ST90728_RS03495 (ST90728_03500) - 650153..651493 (+) 1341 WP_347114466.1 GHKL domain-containing protein -
  ST90728_RS03500 (ST90728_03505) - 651541..651696 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST90728_RS03505 (ST90728_03510) comB 651795..653156 (-) 1362 WP_096811961.1 bacteriocin secretion accessory protein Regulator
  ST90728_RS03510 (ST90728_03515) comA/nlmT 653168..655321 (-) 2154 WP_024404830.1 peptide cleavage/export ABC transporter Regulator
  ST90728_RS03515 (ST90728_03520) - 655619..655876 (+) 258 WP_039671027.1 Blp family class II bacteriocin -
  ST90728_RS03520 (ST90728_03525) - 655893..656087 (+) 195 WP_039671026.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  ST90728_RS03525 (ST90728_03530) - 656690..658041 (+) 1352 WP_096811962.1 IS3 family transposase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 50385.51 Da        Isoelectric Point: 5.2958

>NTDB_id=447576 ST90728_RS03505 WP_096811961.1 651795..653156(-) (comB) [Streptococcus thermophilus strain 90728]
MNPNLFKSAEFYQRRYHNFATHLIVPLILLVGFLLTFSLFAQKEVTVTSRGEITPTTIIASIQSTSNNPITTNNLANNKL
VKKNELIIQYAETMESSQKQALETQLATLNRQKTGLETLKESLSQGTNLFTGEDEFGYINTFNNFITQSQDIELGISKTN
AEVSNQAALAGNTIAAIDTQINQIYHQIAEYEELRQAITNRQTSLSADNPHQATLNNFLAQSQQDSQTGLTDQYLFQINQ
SISGLESSIASLNIQRAGTGSVATYDNSFVTKVEVLRTQFLQSASQQLTTLETQITELVAQLEQASVRLENNTITAPETG
VIHLNSEFEGKSLIPSGSEIAQIYPNINQTKEFLITYYVTSEHVALLKEKQDVRLSLEKVGNQSITVVGKIKSIDKTATK
TEEGNLFKVTALAQLSDKHSDVIQYGLQGRVTSIIAKKTYFDYYKDKILSNHD

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=447576 ST90728_RS03505 WP_096811961.1 651795..653156(-) (comB) [Streptococcus thermophilus strain 90728]
ATGAACCCTAATTTGTTCAAAAGTGCTGAATTTTACCAGCGGCGCTACCATAATTTTGCGACACACTTAATTGTCCCCTT
GATATTATTAGTCGGCTTTCTTCTAACCTTCTCCCTTTTTGCCCAAAAGGAGGTTACCGTCACATCAAGAGGTGAAATTA
CTCCGACGACAATCATCGCTTCCATCCAATCCACCAGCAATAACCCTATCACAACCAATAATCTAGCCAATAACAAGCTG
GTTAAAAAGAATGAGCTCATCATCCAATACGCTGAAACTATGGAGAGTTCCCAAAAACAAGCCCTTGAAACCCAGCTAGC
CACTCTAAATAGACAGAAAACTGGACTTGAAACCCTCAAAGAAAGCCTGTCACAGGGAACGAACCTCTTTACAGGGGAGG
ACGAATTTGGCTATATCAATACTTTTAACAACTTTATCACCCAGTCACAGGACATCGAACTAGGAATTTCCAAAACCAAT
GCAGAGGTGAGTAACCAGGCCGCCCTAGCAGGTAATACCATTGCTGCGATTGACACGCAAATCAATCAAATCTATCACCA
AATAGCAGAATACGAGGAGCTTCGTCAAGCCATTACCAATAGACAGACCAGTTTATCAGCTGACAATCCACACCAAGCCA
CCTTAAACAATTTCTTAGCCCAATCCCAACAAGACTCCCAGACAGGATTAACTGATCAATACCTTTTTCAAATCAACCAA
AGTATCTCAGGGCTAGAATCATCCATAGCTAGTCTGAACATCCAACGAGCTGGAACTGGCTCTGTTGCAACCTATGATAA
CAGCTTTGTAACAAAGGTTGAGGTCCTAAGAACACAGTTTTTACAATCGGCCTCTCAGCAGCTGACCACCCTTGAAACGC
AAATCACAGAGCTAGTGGCACAGCTAGAGCAAGCATCCGTCCGACTAGAAAACAATACCATTACAGCTCCTGAAACAGGG
GTAATCCATCTCAATAGTGAGTTTGAAGGAAAGTCTTTGATTCCAAGCGGTAGTGAAATCGCTCAGATTTACCCCAATAT
CAATCAAACCAAAGAATTCCTCATTACTTACTACGTGACTTCAGAACATGTCGCCTTACTCAAAGAAAAACAAGACGTAC
GCCTGAGCTTAGAAAAAGTTGGCAACCAAAGCATCACTGTTGTTGGAAAAATTAAGTCTATCGATAAAACTGCTACTAAA
ACTGAGGAGGGGAATCTTTTCAAAGTTACTGCCTTGGCTCAACTATCCGACAAGCATAGCGACGTCATCCAGTACGGTCT
CCAGGGTCGAGTCACAAGTATCATTGCCAAGAAGACTTACTTTGATTACTACAAGGATAAAATTTTATCCAACCATGATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

38.444

99.338

0.382
  comB Streptococcus pneumoniae D39

38.444

99.338

0.382
  comB Streptococcus pneumoniae R6

38.444

99.338

0.382
  comB Streptococcus pneumoniae TIGR4

38.222

99.338

0.38
  comB Streptococcus mitis SK321

37.639

99.117

0.373
  comB Streptococcus mitis NCTC 12261

37.639

99.117

0.373