Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   HPY14_RS10955 Genome accession   NZ_CP053798
Coordinates   2448450..2449061 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain SL5Y     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2443450..2454061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPY14_RS10935 (HPY14_10935) - 2443786..2444703 (-) 918 WP_000271067.1 ABC transporter ATP-binding protein -
  HPY14_RS10940 (HPY14_10940) - 2445084..2446730 (-) 1647 WP_000484915.1 SulP family inorganic anion transporter -
  HPY14_RS10945 (HPY14_10945) can 2446878..2447546 (+) 669 WP_001114117.1 carbonate dehydratase -
  HPY14_RS10950 (HPY14_10950) hpt 2447621..2448154 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  HPY14_RS10955 (HPY14_10955) hapR 2448450..2449061 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  HPY14_RS10960 (HPY14_10960) rsmI 2449270..2450136 (-) 867 WP_094392173.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  HPY14_RS10965 (HPY14_10965) - 2450206..2452011 (+) 1806 WP_033930662.1 penicillin-binding protein activator -
  HPY14_RS10970 (HPY14_10970) - 2451998..2452366 (+) 369 WP_001893625.1 YraN family protein -
  HPY14_RS10975 (HPY14_10975) - 2452370..2452960 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  HPY14_RS10980 (HPY14_10980) - 2452963..2453532 (+) 570 WP_000836325.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=447426 HPY14_RS10955 WP_000340100.1 2448450..2449061(+) (hapR) [Vibrio cholerae strain SL5Y]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=447426 HPY14_RS10955 WP_000340100.1 2448450..2449061(+) (hapR) [Vibrio cholerae strain SL5Y]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCATGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709