Detailed information NTG0447300

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GE021_RS11055
• Genome accession: NZ_CP053792
• Coordinates: 2258808..2260031 (+)
• Length: 407 a.a.
• NCBI ID: WP_093999374.1
• Uniprot ID: A0A3P5XRA7
• Organism: Streptococcus canis strain HL_77_1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2253808..2265031

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE021_RS11025 (GE021_011015)	-	2253921..2256500 (+)	2580	WP_125074651.1	YfhO family protein	-
GE021_RS11040 (GE021_011030)	-	2256973..2257797 (-)	825	Protein_2157	DDE-type integrase/transposase/recombinase	-
GE021_RS11050 (GE021_011040)	rlmH	2258117..2258596 (-)	480	WP_125074662.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GE021_RS11055 (GE021_011045)	htrA	2258808..2260031 (+)	1224	WP_093999374.1	trypsin-like peptidase domain-containing protein	Regulator
GE021_RS11060 (GE021_011050)	spo0J	2260128..2260895 (+)	768	WP_125074652.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42616.03 Da
• Isoelectric Point: 5.7603

>NTDB_id=447300 GE021_RS11055 WP_093999374.1 2258808..2260031(+) (htrA) [Streptococcus canis strain HL_77_1]
MPTMKHILKFLGITLIGFLGGILAIVTVNNTSQQSSSTSHSGSATTSKMVFNNTTDTTKAVNVIQNAVVSVINYQDDPSS
SLSNPYIKLFGEDQAKENKDAELTIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTIAEFADSSKLNVGEVAIAIGSPLGTQYANSVTEGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGNNGNSGAVEGIGFAIPSSDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALRQ
INIPTSVTGGIVVASVQAGMPATGKLTQYDVITEIDGKAVNSISDLQSNLYGHNINDTIKVTFYRGTAKKKADIKLTKTT
QDLSKAQ

Nucleotide

• Length: 1224 bp

>NTDB_id=447300 GE021_RS11055 WP_093999374.1 2258808..2260031(+) (htrA) [Streptococcus canis strain HL_77_1]
ATGCCCACTATGAAACATATCTTAAAATTCTTAGGTATTACACTCATCGGATTTTTAGGAGGAATCTTGGCTATTGTTAC
AGTTAATAATACTAGTCAACAATCTTCTTCTACGTCACACTCAGGTAGTGCAACAACCAGTAAAATGGTTTTCAATAATA
CCACTGATACTACAAAAGCTGTTAACGTTATTCAAAATGCAGTGGTATCCGTTATTAATTATCAAGATGATCCTTCTTCA
TCTTTGTCTAATCCTTACATAAAACTTTTTGGAGAGGATCAGGCAAAAGAAAATAAGGATGCTGAACTAACAATTTTTAG
CGAAGGTTCTGGTGTCATTTATCGAAAAGACGGTAATTCTGCCTATGTTGTTACTAATAATCACGTTATTGATGGTGCTA
AGCGCATTGAAATCCTTATGGCTGATGGATCTAAAGTGGTTGGGGAATTAGTCGGCGCTGATACCTATTCTGACTTAGCA
GTTGTCAAAATTTCTTCTGATAAGATTAAAACAATCGCGGAATTTGCTGATTCAAGCAAACTTAATGTTGGAGAAGTAGC
TATTGCTATAGGTAGTCCTTTAGGAACTCAATATGCCAATTCTGTCACCGAAGGGATTGTTTCAAGTCTCAGTCGTACTG
TTACCTTAAAAAATGAAAATGGTGAAACTGTTTCAACCAATGCTATTCAAACAGACGCTGCCATTAATCCAGGAAACTCT
GGTGGTCCACTCATTAATATCGAAGGACAAGTCATCGGAATTAATTCAAGTAAAATCTCCTCTACACCAACTGGTAATAA
TGGAAATAGCGGAGCTGTCGAAGGAATCGGCTTTGCTATTCCATCTAGTGATGTTATCAAAATTATCAAGCAATTAGAAA
CCAATGGGGAAGTCATCAGACCTGCCCTTGGTATTTCTATGGTTAACTTAAATGATTTATCAACCAATGCCCTTCGTCAA
ATCAATATTCCAACTAGTGTGACAGGTGGGATTGTAGTCGCTTCTGTTCAAGCTGGCATGCCAGCTACAGGTAAACTTAC
TCAATACGATGTGATTACCGAAATCGATGGTAAAGCCGTCAACTCAATTAGTGATCTTCAAAGTAATTTATATGGACACA
ACATTAATGATACTATCAAAGTAACCTTTTACAGAGGAACAGCAAAGAAAAAAGCAGACATCAAATTAACGAAGACTACA
CAAGATTTAAGTAAAGCGCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• PDZ domain (PDZ_2) (301-396)

3D structure

• AlphaFold DB: A0A3P5XRA7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.794	99.017	0.602
htrA	Streptococcus mitis NCTC 12261	54.3	100	0.543
htrA	Streptococcus pneumoniae Rx1	54.3	100	0.543
htrA	Streptococcus pneumoniae D39	54.3	100	0.543
htrA	Streptococcus pneumoniae R6	54.3	100	0.543
htrA	Streptococcus pneumoniae TIGR4	54.3	100	0.543
htrA	Streptococcus gordonii str. Challis substr. CH1	54.975	98.771	0.543