Detailed information NTG0447187

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GE023_RS10730
• Genome accession: NZ_CP053789
• Coordinates: 2173936..2175159 (+)
• Length: 407 a.a.
• NCBI ID: WP_093999374.1
• Uniprot ID: A0A3P5XRA7
• Organism: Streptococcus canis strain HL_98_2
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2168936..2180159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE023_RS10700 (GE023_010695)	recF	2169380..2170483 (-)	1104	WP_093999512.1	DNA replication/repair protein RecF	-
GE023_RS10705 (GE023_010700)	yaaA	2170485..2170898 (-)	414	WP_093999511.1	S4 domain-containing protein YaaA	-
GE023_RS10710 (GE023_010705)	-	2170978..2171877 (-)	900	Protein_2073	IS30 family transposase	-
GE023_RS10715 (GE023_010710)	-	2172100..2172924 (-)	825	Protein_2074	DDE-type integrase/transposase/recombinase	-
GE023_RS10725 (GE023_010720)	rlmH	2173244..2173723 (-)	480	WP_093999375.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GE023_RS10730 (GE023_010725)	htrA	2173936..2175159 (+)	1224	WP_093999374.1	trypsin-like peptidase domain-containing protein	Regulator
GE023_RS10735 (GE023_010730)	spo0J	2175256..2176023 (+)	768	WP_093999373.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42616.03 Da
• Isoelectric Point: 5.7603

>NTDB_id=447187 GE023_RS10730 WP_093999374.1 2173936..2175159(+) (htrA) [Streptococcus canis strain HL_98_2]
MPTMKHILKFLGITLIGFLGGILAIVTVNNTSQQSSSTSHSGSATTSKMVFNNTTDTTKAVNVIQNAVVSVINYQDDPSS
SLSNPYIKLFGEDQAKENKDAELTIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTIAEFADSSKLNVGEVAIAIGSPLGTQYANSVTEGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGNNGNSGAVEGIGFAIPSSDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALRQ
INIPTSVTGGIVVASVQAGMPATGKLTQYDVITEIDGKAVNSISDLQSNLYGHNINDTIKVTFYRGTAKKKADIKLTKTT
QDLSKAQ

Nucleotide

• Length: 1224 bp

>NTDB_id=447187 GE023_RS10730 WP_093999374.1 2173936..2175159(+) (htrA) [Streptococcus canis strain HL_98_2]
ATGCCCACTATGAAACATATCTTAAAATTCTTAGGTATTACACTCATCGGATTTTTAGGAGGAATCTTGGCTATTGTTAC
AGTTAATAATACTAGTCAACAATCTTCTTCTACGTCACACTCAGGTAGTGCAACAACCAGTAAAATGGTTTTCAATAATA
CCACTGATACTACAAAAGCTGTTAACGTTATTCAAAATGCAGTGGTATCCGTTATTAATTATCAAGATGATCCTTCTTCA
TCTTTGTCTAATCCTTACATAAAACTTTTTGGAGAGGATCAGGCAAAAGAAAATAAGGATGCTGAACTAACAATTTTTAG
CGAAGGTTCTGGTGTCATTTATCGAAAAGACGGTAATTCTGCCTATGTTGTTACTAATAATCACGTTATTGATGGTGCTA
AGCGCATTGAAATCCTTATGGCTGATGGATCTAAAGTGGTTGGGGAATTAGTCGGCGCTGATACCTATTCTGACTTAGCA
GTTGTCAAAATTTCTTCTGATAAGATTAAAACAATCGCGGAATTTGCTGATTCAAGCAAACTTAATGTTGGAGAAGTAGC
TATTGCTATAGGTAGTCCTTTAGGAACTCAATATGCCAATTCTGTCACCGAAGGGATTGTTTCAAGTCTCAGTCGTACTG
TTACCTTAAAAAATGAAAATGGTGAAACTGTTTCAACCAATGCTATTCAAACAGACGCTGCCATTAATCCAGGAAACTCT
GGTGGTCCACTCATTAATATCGAAGGACAAGTCATCGGAATTAATTCAAGTAAAATTTCCTCTACACCAACTGGTAATAA
TGGTAATAGCGGAGCTGTCGAAGGAATCGGCTTTGCTATTCCATCTAGTGATGTTATCAAAATTATCAAGCAATTAGAAA
CCAATGGAGAAGTCATCAGACCTGCCCTTGGTATCTCTATGGTTAACTTAAATGATTTATCAACCAATGCCCTTCGTCAA
ATCAATATTCCAACTAGTGTGACAGGTGGGATTGTAGTCGCTTCTGTTCAAGCTGGCATGCCAGCTACAGGTAAACTTAC
TCAGTACGATGTGATTACCGAAATCGATGGTAAAGCCGTCAACTCAATTAGTGATCTTCAAAGTAATTTATATGGACATA
ACATTAATGATACTATCAAAGTAACCTTTTACAGAGGGACAGCAAAGAAAAAAGCAGACATCAAATTAACGAAGACTACA
CAAGATTTAAGTAAAGCGCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• PDZ domain (PDZ_2) (301-396)

3D structure

• AlphaFold DB: A0A3P5XRA7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.794	99.017	0.602
htrA	Streptococcus mitis NCTC 12261	54.3	100	0.543
htrA	Streptococcus pneumoniae Rx1	54.3	100	0.543
htrA	Streptococcus pneumoniae D39	54.3	100	0.543
htrA	Streptococcus pneumoniae R6	54.3	100	0.543
htrA	Streptococcus pneumoniae TIGR4	54.3	100	0.543
htrA	Streptococcus gordonii str. Challis substr. CH1	54.975	98.771	0.543