Detailed information NTG0447013

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: I5V48_RS06295
• Genome accession: NZ_CP065430
• Coordinates: 1287583..1288425 (+)
• Length: 280 a.a.
• NCBI ID: WP_014638936.1
• Uniprot ID: -
• Organism: Streptococcus suis strain YZDH1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1282583..1293425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I5V48_RS06265 (I5V48_06265)	-	1283418..1284197 (+)	780	WP_043026878.1	ribonuclease HII	-
I5V48_RS06270 (I5V48_06270)	-	1284194..1285204 (+)	1011	WP_043026879.1	YdcF family protein	-
I5V48_RS06275 (I5V48_06275)	trhA	1285237..1285887 (-)	651	WP_043026880.1	PAQR family membrane homeostasis protein TrhA	-
I5V48_RS06280 (I5V48_06280)	-	1285877..1286428 (-)	552	WP_014638939.1	DUF1836 domain-containing protein	-
I5V48_RS06285 (I5V48_06285)	-	1286525..1286836 (-)	312	WP_014638938.1	rhodanese-like domain-containing protein	-
I5V48_RS06290 (I5V48_06290)	-	1286965..1287522 (+)	558	WP_014638937.1	sugar O-acetyltransferase	-
I5V48_RS06295 (I5V48_06295)	dprA	1287583..1288425 (+)	843	WP_014638936.1	DNA-processing protein DprA	Machinery gene
I5V48_RS06300 (I5V48_06300)	topA	1288518..1290611 (+)	2094	WP_197314989.1	type I DNA topoisomerase	-
I5V48_RS06305 (I5V48_06305)	rplJ	1291126..1291620 (+)	495	WP_197314990.1	50S ribosomal protein L10	-
I5V48_RS06310 (I5V48_06310)	rplL	1291686..1292051 (+)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
I5V48_RS06315 (I5V48_06315)	-	1292176..1292925 (+)	750	WP_014638934.1	HAD family hydrolase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31347.20 Da
• Isoelectric Point: 8.2214

>NTDB_id=447013 I5V48_RS06295 WP_014638936.1 1287583..1288425(+) (dprA) [Streptococcus suis strain YZDH1]
MNNFELFKWKKAGLTNLNVNKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELSNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKIYPKENRELQTYIGKHHLVLTEYEPDADPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCVTSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=447013 I5V48_RS06295 WP_014638936.1 1287583..1288425(+) (dprA) [Streptococcus suis strain YZDH1]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAATGTGAATAAAGTTTTGGCCTATCAAGA
AAAACACGGAAAAAAATTGACCTTGCGAAATGTCGCTGTAGTATCTGAATGTAAAAATCCAGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
CTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTACCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAAGAATTGAGCAATCGTT
TTGTCATTGTTAGTGGTTTGGCAAGAGGAATTGATACAGCAGCCCACATCGCCAGTTTGAAAAATGGAGGCCAAACCATT
GCCGTTATTGGAACAGGTTTGGATAAGATTTATCCCAAAGAAAACAGAGAATTGCAGACCTACATAGGTAAACACCATTT
AGTTTTGACTGAATATGAACCAGATGCAGACCCTCTCAAATACCATTTTCCAGAACGCAATCGCATTATAGCTGGTTTGG
TAGAAGGATTGGTAGTCTGTGAGGCAAAAATGCGGTCTGGTAGCTTGATTACCTGCGAACGTGCCTTGGAAGAAGGCAGA
GAAGTCTATGCTATTCCAGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGAGCAAAGTG
CGTTACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	69.643	100	0.696
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.857	100	0.629
dprA/cilB/dalA	Streptococcus mitis SK321	62.857	100	0.629
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.857	100	0.629
dprA	Lactococcus lactis subsp. cremoris KW2	60	100	0.6
dprA	Legionella pneumophila strain ERS1305867	42.105	88.214	0.371
dprA	Bacillus subtilis subsp. subtilis str. 168	51.244	71.786	0.368