Detailed information NTG0044531

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS1882_RS04265
• Genome accession: NC_017053
• Coordinates: 864513..865349 (+)
• Length: 278 a.a.
• NCBI ID: WP_014407585.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS1882
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 859513..870349

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS1882_RS04235 (MGAS1882_0872)	-	860064..860435 (+)	372	WP_014407581.1	hypothetical protein	-
MGAS1882_RS04240 (MGAS1882_0873)	-	860485..861396 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
MGAS1882_RS04245 (MGAS1882_0874)	trhA	861513..862163 (-)	651	WP_014407582.1	PAQR family membrane homeostasis protein TrhA	-
MGAS1882_RS04250 (MGAS1882_0875)	-	862160..862600 (-)	441	WP_014407583.1	DUF1836 domain-containing protein	-
MGAS1882_RS04255 (MGAS1882_0876)	ylqF	862819..863667 (+)	849	WP_014407584.1	ribosome biogenesis GTPase YlqF	-
MGAS1882_RS04260 (MGAS1882_0877)	-	863657..864448 (+)	792	WP_002995007.1	ribonuclease HII	-
MGAS1882_RS04265 (MGAS1882_0878)	dprA	864513..865349 (+)	837	WP_014407585.1	DNA-processing protein DprA	Machinery gene
MGAS1882_RS04270 (MGAS1882_0879)	topA	865457..867586 (+)	2130	WP_014407586.1	type I DNA topoisomerase	-
MGAS1882_RS09265	-	867661..868518 (-)	858	Protein_809	LysR family transcriptional regulator	-
MGAS1882_RS04280 (MGAS1882_0882)	-	868558..869124 (+)	567	Protein_810	PTS sugar transporter subunit IIC	-
MGAS1882_RS04285 (MGAS1882_0883)	-	869139..870131 (+)	993	WP_009880715.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=44531 MGAS1882_RS04265 WP_014407585.1 864513..865349(+) (dprA) [Streptococcus pyogenes MGAS1882]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=44531 MGAS1882_RS04265 WP_014407585.1 864513..865349(+) (dprA) [Streptococcus pyogenes MGAS1882]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367