Detailed information NTG0044401

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: MGAS15252_RS04285
• Genome accession: NC_017040
• Coordinates: 867013..867849 (+)
• Length: 278 a.a.
• NCBI ID: WP_014407585.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS15252
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 862013..872849

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS15252_RS04255 (MGAS15252_0877)	-	862564..862935 (+)	372	WP_014407581.1	hypothetical protein	-
MGAS15252_RS04260 (MGAS15252_0878)	-	862985..863896 (-)	912	WP_002989777.1	diacylglycerol/lipid kinase family protein	-
MGAS15252_RS04265 (MGAS15252_0879)	trhA	864013..864663 (-)	651	WP_014407582.1	PAQR family membrane homeostasis protein TrhA	-
MGAS15252_RS04270 (MGAS15252_0880)	-	864660..865100 (-)	441	WP_014407583.1	DUF1836 domain-containing protein	-
MGAS15252_RS04275 (MGAS15252_0881)	ylqF	865319..866167 (+)	849	WP_014407584.1	ribosome biogenesis GTPase YlqF	-
MGAS15252_RS04280 (MGAS15252_0882)	-	866157..866948 (+)	792	WP_002995007.1	ribonuclease HII	-
MGAS15252_RS04285 (MGAS15252_0883)	dprA	867013..867849 (+)	837	WP_014407585.1	DNA-processing protein DprA	Machinery gene
MGAS15252_RS04290 (MGAS15252_0884)	topA	867957..870086 (+)	2130	WP_014407586.1	type I DNA topoisomerase	-
MGAS15252_RS09085	-	870161..871018 (-)	858	Protein_813	LysR family transcriptional regulator	-
MGAS15252_RS04300 (MGAS15252_0887)	-	871058..871624 (+)	567	Protein_814	PTS sugar transporter subunit IIC	-
MGAS15252_RS04305 (MGAS15252_0888)	-	871639..872631 (+)	993	WP_009880715.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=44401 MGAS15252_RS04285 WP_014407585.1 867013..867849(+) (dprA) [Streptococcus pyogenes MGAS15252]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=44401 MGAS15252_RS04285 WP_014407585.1 867013..867849(+) (dprA) [Streptococcus pyogenes MGAS15252]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367