NTDB

Overview

Name	comGF	Type	Machinery gene
Locus tag	HLG72_RS07805	Genome accession	NZ_CP053185
Coordinates	1615840..1616337 (-)	Length	165 a.a.
NCBI ID	WP_001838632.1	Uniprot ID	A0A6A9GZK7
Organism	Staphylococcus aureus strain Guangzhou-SAU749
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1610840..1621337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLG72_RS07780 (HLG72_07780)	gcvPB	1611002..1612474 (-)	1473	WP_000202177.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPB	-
HLG72_RS07785 (HLG72_07785)	gcvPA	1612467..1613813 (-)	1347	WP_000019687.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-
HLG72_RS07790 (HLG72_07790)	gcvT	1613833..1614924 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
HLG72_RS07795 (HLG72_07795)	-	1615083..1615607 (-)	525	WP_001015116.1	shikimate kinase	-
HLG72_RS07800 (HLG72_07800)	-	1615597..1615743 (-)	147	WP_001789879.1	hypothetical protein	-
HLG72_RS07805 (HLG72_07805)	comGF	1615840..1616337 (-)	498	WP_001838632.1	competence type IV pilus minor pilin ComGF	Machinery gene
HLG72_RS07810 (HLG72_07810)	comGE	1616255..1616554 (-)	300	WP_000844413.1	hypothetical protein	Machinery gene
HLG72_RS07815 (HLG72_07815)	comGD	1616541..1616987 (-)	447	WP_001796473.1	competence type IV pilus minor pilin ComGD	Machinery gene
HLG72_RS07820 (HLG72_07820)	comGC	1616965..1617276 (-)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
HLG72_RS07825 (HLG72_07825)	comGB	1617290..1618360 (-)	1071	WP_000776407.1	competence type IV pilus assembly protein ComGB	Machinery gene
HLG72_RS07830 (HLG72_07830)	comGA	1618332..1619306 (-)	975	WP_000697218.1	competence type IV pilus ATPase ComGA	Machinery gene
HLG72_RS07835 (HLG72_07835)	-	1619358..1619981 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
HLG72_RS07840 (HLG72_07840)	-	1619978..1620307 (-)	330	WP_170833565.1	MTH1187 family thiamine-binding protein	-
HLG72_RS07845 (HLG72_07845)	-	1620307..1621293 (-)	987	WP_000161315.1	ROK family glucokinase	-

Sequence

Protein

Download Length: 165 a.a. Molecular weight: 19184.87 Da Isoelectric Point: 10.2192

                                >NTDB_id=443328 HLG72_RS07805 WP_001838632.1 1615840..1616337(-) (comGF) [Staphylococcus aureus strain Guangzhou-SAU749]

MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVISITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDI

LEDFKGVDRNNIENREQRIILHKGEEMIEYKLINNKIIKVVNDRGNITMINNVTAFTANIYYKSIIKITITVKVGTNVQT

KTIYV

Nucleotide

Download Length: 498 bp

                                >NTDB_id=443328 HLG72_RS07805 WP_001838632.1 1615840..1616337(-) (comGF) [Staphylococcus aureus strain Guangzhou-SAU749]

ATGATATTAAGCAAAGTGACCAACAAATTTGTGCTATTTCAAAAAATACCACTTCTTATCAAAAGACATGTATACAGTAT

TAATGTCAAAGCTTTTTCTCTCATTGAAATGTTAGTAGCGATGATGGTTATAAGTATAACTTTACTAATTGTTCCAGACT

TAATTAGACTTAGCAAAACTTTTCTAATTGAAAGTAGGGAATTAACAACTGTAGATTTCGAATTTTTCTCAAGAGATATT

CTAGAGGATTTTAAAGGAGTAGATAGAAACAATATTGAAAATAGGGAACAGCGTATCATTTTACATAAAGGTGAAGAAAT

GATCGAATACAAATTAATAAATAATAAAATTATTAAAGTTGTAAATGACAGAGGAAATATAACAATGATTAATAATGTTA

CAGCATTTACTGCAAATATCTACTATAAATCCATTATTAAAATAACGATAACAGTTAAAGTCGGTACAAATGTGCAGACT

AAAACTATTTATGTATAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(68-155)

Prokaryotic N-terminal methylation motif (N_methyl)

(28-51)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A6A9GZK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGF	Staphylococcus aureus N315	96.364	100	0.964
comGF	Staphylococcus aureus MW2	96.364	100	0.964

Detailed information NTG0443328