Detailed information NTG0442772

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: HHM66_RS02930
• Genome accession: NZ_CP053074
• Coordinates: 554064..555416 (+)
• Length: 450 a.a.
• NCBI ID: WP_014612101.1
• Uniprot ID: A0AB38Y2E7
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 549064..560416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM66_RS02905 (HHM66_02910)	-	550131..550778 (-)	648	WP_003057245.1	amino acid ABC transporter permease	-
HHM66_RS02910 (HHM66_02915)	-	550793..551494 (-)	702	WP_015057398.1	amino acid ABC transporter permease	-
HHM66_RS02915 (HHM66_02920)	-	551508..552308 (-)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
HHM66_RS02920 (HHM66_02925)	-	552308..553102 (-)	795	WP_015057400.1	amino acid ABC transporter ATP-binding protein	-
HHM66_RS02925 (HHM66_02930)	vicR	553361..554071 (+)	711	WP_003057225.1	response regulator YycF	Regulator
HHM66_RS02930 (HHM66_02935)	vicK	554064..555416 (+)	1353	WP_014612101.1	cell wall metabolism sensor histidine kinase VicK	Regulator
HHM66_RS02935 (HHM66_02940)	vicX	555420..556229 (+)	810	WP_003059746.1	MBL fold metallo-hydrolase	Regulator
HHM66_RS02940 (HHM66_02945)	rnc	556987..557679 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.06 Da
• Isoelectric Point: 5.7411

>NTDB_id=442772 HHM66_RS02930 WP_014612101.1 554064..555416(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=442772 HHM66_RS02930 WP_014612101.1 554064..555416(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-165)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.188	92	0.673
micB	Streptococcus pneumoniae Cp1015	66.588	94.444	0.629