Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   HHJ58_RS06590 Genome accession   NZ_CP051640
Coordinates   1433324..1434646 (-) Length   440 a.a.
NCBI ID   WP_035688106.1    Uniprot ID   -
Organism   Avibacterium paragallinarum strain ADL-AP07     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1435014..1445870 1433324..1434646 flank 368


Gene organization within MGE regions


Location: 1433324..1445870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHJ58_RS06590 (HHJ58_06590) comE 1433324..1434646 (-) 1323 WP_035688106.1 type IV pilus secretin PilQ Machinery gene
  HHJ58_RS06595 (HHJ58_06595) - 1434655..1435014 (-) 360 WP_017806828.1 hypothetical protein -
  HHJ58_RS06600 (HHJ58_06600) - 1435014..1435562 (-) 549 WP_168952572.1 hypothetical protein -
  HHJ58_RS06605 (HHJ58_06605) - 1435528..1436040 (-) 513 WP_046097217.1 PilN domain-containing protein -
  HHJ58_RS06610 (HHJ58_06610) - 1436070..1436837 (-) 768 WP_035688099.1 hypothetical protein -
  HHJ58_RS06615 (HHJ58_06615) - 1436996..1439545 (+) 2550 WP_035688097.1 penicillin-binding protein 1A -
  HHJ58_RS06620 (HHJ58_06620) - 1439812..1440465 (+) 654 WP_035688094.1 IS1595 family transposase -
  HHJ58_RS06625 (HHJ58_06625) hmpA 1440709..1441908 (-) 1200 WP_035688092.1 NO-inducible flavohemoprotein -
  HHJ58_RS06630 (HHJ58_06630) - 1442047..1442475 (+) 429 WP_017806833.1 Rrf2 family transcriptional regulator -
  HHJ58_RS06635 (HHJ58_06635) glyS 1442594..1444657 (-) 2064 WP_035688090.1 glycine--tRNA ligase subunit beta -
  HHJ58_RS06640 (HHJ58_06640) - 1444683..1445288 (-) 606 WP_035688088.1 hypothetical protein -
  HHJ58_RS06645 (HHJ58_06645) - 1445487..1445870 (-) 384 WP_035688085.1 endonuclease domain-containing protein -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 48606.59 Da        Isoelectric Point: 6.1204

>NTDB_id=440116 HHJ58_RS06590 WP_035688106.1 1433324..1434646(-) (comE) [Avibacterium paragallinarum strain ADL-AP07]
MKLPNIIKNILLFFLILSYPFRQVNASDENNTFSVHLKQAPLVDTVQYLAGYQKINLVIDDELSGSISLQLQNTTLLQLL
KSIAEIKHLRFWENNGIYYLSQSQATNQENVVLNSSTEIATSADMLITSIKLHYAKASEVMKALTSGNGSLLTANGSISF
DERNNLLIIQDEAKKIKQIRKLVADMDKPIQQIIIEARIVTISDESLKELGVRWGIFSPSDISHSVSGSLNANGFSNITD
NLNINFATSSNPAGSVALQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVNNGKNDTQSIE
FREAVLGLEVTPHLLKHNGILLDLVVSQNAPGGRVSYGENEVISIDKQEINTQVFAQDGETIVLGGIFHDTITKALDKVP
ILGDIPGIKRLFSKEVERHQKRELVIFVTPRLIRSGTVEE

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=440116 HHJ58_RS06590 WP_035688106.1 1433324..1434646(-) (comE) [Avibacterium paragallinarum strain ADL-AP07]
ATGAAGTTACCAAATATAATAAAGAATATTCTTTTATTTTTTCTTATTCTATCCTATCCATTTAGACAGGTTAATGCAAG
TGACGAAAATAATACATTCTCTGTTCATTTAAAGCAGGCTCCATTAGTAGATACTGTACAATATTTAGCTGGGTATCAAA
AAATCAATTTAGTCATAGATGATGAATTGTCTGGTTCAATATCTTTGCAATTGCAAAATACAACATTACTTCAATTATTA
AAATCTATCGCTGAAATCAAACATTTGCGGTTTTGGGAAAATAATGGGATATATTATTTAAGTCAGTCGCAAGCAACTAA
TCAAGAAAATGTAGTGTTAAATTCATCAACAGAAATAGCAACATCAGCAGATATGTTAATAACTTCAATAAAGTTGCACT
ATGCCAAAGCATCCGAGGTAATGAAAGCCCTCACTTCAGGGAATGGCTCTTTATTAACAGCAAATGGAAGTATAAGTTTT
GATGAACGCAATAATTTACTCATTATCCAAGATGAAGCTAAAAAAATAAAACAAATTAGGAAATTGGTAGCGGATATGGA
TAAACCCATTCAGCAAATTATTATTGAAGCTCGTATTGTCACAATTAGCGATGAAAGTTTAAAAGAATTGGGAGTCAGAT
GGGGAATTTTTTCTCCCTCAGATATAAGCCATAGCGTTTCTGGAAGTTTAAATGCAAATGGATTCTCAAATATTACGGAT
AATCTAAATATTAATTTTGCGACGAGTTCAAATCCTGCAGGTTCGGTAGCTTTGCAAGTAGCTAAAATTAATGGAAGGTT
ATTAGATTTAGAGTTGACAGCATTAGAAAGAGAAAATAACGTTGAAATTATTGCGAGTCCACGATTATTGACCACAAATA
AGAAAAGTGCAAGTATCAAGCAAGGTACAGAAATCCCCTATGTAGTGAATAATGGAAAAAATGATACGCAGTCTATTGAA
TTCCGAGAAGCTGTACTTGGGCTTGAAGTTACACCTCATTTATTAAAGCATAACGGTATTTTACTTGATCTTGTTGTTAG
TCAGAATGCACCTGGAGGACGAGTATCTTATGGAGAAAATGAGGTGATTTCTATTGATAAACAGGAAATTAATACGCAAG
TCTTTGCACAAGACGGCGAAACGATTGTATTGGGCGGAATTTTCCACGATACGATTACTAAAGCACTTGATAAAGTACCA
ATTTTAGGAGACATACCTGGAATAAAAAGGCTATTTAGTAAGGAAGTCGAGAGACATCAAAAGAGGGAACTCGTTATTTT
TGTTACACCACGCTTAATTCGTAGTGGTACAGTAGAGGAATGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(129-192)

Bacterial type II and III secretion system protein (Secretin)

(274-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

65.023

96.818

0.63
  comE Haemophilus influenzae 86-028NP

64.789

96.818

0.627
  comE Glaesserella parasuis strain SC1401

49.883

97.045

0.484
  pilQ Vibrio campbellii strain DS40M4

40

96.591

0.386
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

40.288

94.773

0.382
  pilQ Vibrio cholerae strain A1552

40.288

94.773

0.382