Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   YYK_RS04710 Genome accession   NC_018526
Coordinates   954833..955504 (-) Length   223 a.a.
NCBI ID   WP_009909965.1    Uniprot ID   -
Organism   Streptococcus suis S735     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 949833..960504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  YYK_RS04685 (YYK_04450) coaA 950412..951332 (+) 921 WP_012027068.1 type I pantothenate kinase -
  YYK_RS04690 (YYK_04455) rpsT 951391..951639 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  YYK_RS04695 (YYK_04460) - 951901..953130 (-) 1230 WP_014735785.1 transglutaminase domain-containing protein -
  YYK_RS04705 (YYK_04470) ciaH 953461..954840 (-) 1380 WP_012775588.1 sensor histidine kinase Regulator
  YYK_RS04710 (YYK_04475) ciaR 954833..955504 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  YYK_RS04715 (YYK_04480) - 955698..956078 (-) 381 WP_012027076.1 hypothetical protein -
  YYK_RS04720 (YYK_04485) - 956452..957654 (+) 1203 WP_014917250.1 IS110 family transposase -
  YYK_RS04725 (YYK_04490) phoU 957856..958512 (-) 657 WP_012028219.1 phosphate signaling complex protein PhoU -
  YYK_RS04730 (YYK_04495) pstB 958541..959299 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  YYK_RS04735 (YYK_04500) pstB 959311..960114 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25290.00 Da        Isoelectric Point: 4.2183

>NTDB_id=43985 YYK_RS04710 WP_009909965.1 954833..955504(-) (ciaR) [Streptococcus suis S735]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=43985 YYK_RS04710 WP_009909965.1 954833..955504(-) (ciaR) [Streptococcus suis S735]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT
TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.135

100

0.901
  ciaR Streptococcus pneumoniae Rx1

88.341

100

0.883
  ciaR Streptococcus pneumoniae D39

88.341

100

0.883
  ciaR Streptococcus pneumoniae R6

88.341

100

0.883
  ciaR Streptococcus pneumoniae TIGR4

88.341

100

0.883
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.39
  vicR Streptococcus mutans UA159

35.47

100

0.372
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.363

Multiple sequence alignment