Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IMP66_RS09405 Genome accession   NZ_CP062883
Coordinates   1965057..1965713 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Res13-Lact-PEA06-10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1960057..1970713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMP66_RS09375 (IMP66_09385) dcyD 1960936..1961922 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  IMP66_RS09380 (IMP66_09390) tcyL 1961937..1962605 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  IMP66_RS09385 (IMP66_09395) tcyN 1962602..1963354 (+) 753 WP_100003997.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IMP66_RS09390 (IMP66_09400) sdiA 1963584..1964306 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  IMP66_RS09395 (IMP66_09405) yecF 1964374..1964598 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  IMP66_RS09400 (IMP66_09410) yecU 1964585..1964761 (-) 177 WP_000590344.1 protein YecU -
  IMP66_RS25455 - 1964799..1964915 (-) 117 Protein_1861 transcriptional regulator -
  IMP66_RS09405 (IMP66_09415) letA 1965057..1965713 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IMP66_RS09410 (IMP66_09420) uvrC 1965710..1967542 (+) 1833 WP_195686572.1 excinuclease ABC subunit UvrC Machinery gene
  IMP66_RS09415 (IMP66_09425) pgsA 1967599..1968147 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IMP66_RS09435 (IMP66_09445) yecA 1968797..1969462 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=435349 IMP66_RS09405 WP_000611335.1 1965057..1965713(+) (letA) [Escherichia coli strain Res13-Lact-PEA06-10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=435349 IMP66_RS09405 WP_000611335.1 1965057..1965713(+) (letA) [Escherichia coli strain Res13-Lact-PEA06-10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486