Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   HB751_RS08955 Genome accession   NZ_CP050272
Coordinates   1834516..1835547 (+) Length   343 a.a.
NCBI ID   WP_255262721.1    Uniprot ID   -
Organism   Streptococcus mutans strain P6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1829516..1840547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB751_RS08945 (HB751_08945) - 1833126..1833509 (+) 384 WP_002263434.1 DUF1033 family protein -
  HB751_RS08950 (HB751_08950) comYA 1833639..1834580 (+) 942 WP_019804919.1 competence type IV pilus ATPase ComGA Machinery gene
  HB751_RS08955 (HB751_08955) comYB 1834516..1835547 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  HB751_RS08960 (HB751_08960) comYC 1835547..1835861 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  HB751_RS08965 (HB751_08965) comYD 1835848..1836252 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  HB751_RS08970 (HB751_08970) comYE 1836224..1836517 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  HB751_RS08975 (HB751_08975) comYF 1836504..1836938 (+) 435 WP_002274770.1 competence type IV pilus minor pilin ComGF Machinery gene
  HB751_RS08980 (HB751_08980) comYG 1836916..1837305 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  HB751_RS08985 (HB751_08985) comYH 1837360..1838313 (+) 954 WP_019317550.1 class I SAM-dependent methyltransferase Machinery gene
  HB751_RS08990 (HB751_08990) - 1838372..1839571 (+) 1200 WP_002263443.1 acetate kinase -
  HB751_RS08995 (HB751_08995) tnpA 1839784..1840247 (+) 464 Protein_1739 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39844.46 Da        Isoelectric Point: 9.5151

>NTDB_id=431208 HB751_RS08955 WP_255262721.1 1834516..1835547(+) (comYB) [Streptococcus mutans strain P6]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=431208 HB751_RS08955 WP_255262721.1 1834516..1835547(+) (comYB) [Streptococcus mutans strain P6]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGTATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

100

100

1
  comYB Streptococcus mutans UA140

99.417

100

0.994
  comYB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507