Detailed information NTG0431141

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: HB752_RS08060
• Genome accession: NZ_CP050271
• Coordinates: 1648701..1650983 (-)
• Length: 760 a.a.
• NCBI ID: WP_002266017.1
• Uniprot ID: A0AAX1K0V4
• Organism: Streptococcus mutans strain S1
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1643701..1655983

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB752_RS08045 (HB752_08045)	ulaG	1644090..1645181 (-)	1092	WP_002263526.1	L-ascorbate 6-phosphate lactonase	-
HB752_RS08050 (HB752_08050)	-	1645761..1647428 (-)	1668	WP_002263525.1	transcription antiterminator	-
HB752_RS08055 (HB752_08055)	comB/nlmE	1647785..1648687 (-)	903	WP_167311854.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
HB752_RS08060 (HB752_08060)	comA/nlmT	1648701..1650983 (-)	2283	WP_002266017.1	peptide cleavage/export ABC transporter	Regulator
HB752_RS08065 (HB752_08065)	-	1652247..1652525 (-)	279	WP_002264456.1	hypothetical protein	-
HB752_RS08070 (HB752_08070)	-	1652763..1652972 (-)	210	WP_002263944.1	hypothetical protein	-
HB752_RS08075 (HB752_08075)	-	1653457..1653618 (-)	162	WP_162470319.1	hypothetical protein	-
HB752_RS08080 (HB752_08080)	-	1653885..1654292 (-)	408	WP_002270936.1	hypothetical protein	-
HB752_RS08085 (HB752_08085)	-	1654311..1654529 (-)	219	WP_002309575.1	Blp family class II bacteriocin	-
HB752_RS08090 (HB752_08090)	-	1654810..1655085 (-)	276	WP_167311806.1	hypothetical protein	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85082.76 Da
• Isoelectric Point: 8.9095

>NTDB_id=431141 HB752_RS08060 WP_002266017.1 1648701..1650983(-) (comA/nlmT) [Streptococcus mutans strain S1]
MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRHISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=431141 HB752_RS08060 WP_002266017.1 1648701..1650983(-) (comA/nlmT) [Streptococcus mutans strain S1]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGATCTAACTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTAATTCTGGTTGGCGGAGTTTTATTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCTATTCCGATTTATGCCATCATTATTTTTGCTTTCTTAAAGCCTTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTCTGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAGGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGCGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAAACAACTTTGGCTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGCATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAGGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACACAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAGGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (50-186)

• ABC transporter (ABC_tran) (544-693)

• ABC transporter transmembrane region (ABC_membrane) (212-481)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	99.868	100	0.999
comA	Streptococcus mitis NCTC 12261	65.411	94.342	0.617
comA	Streptococcus pneumoniae Rx1	64.854	94.342	0.612
comA	Streptococcus pneumoniae D39	64.854	94.342	0.612
comA	Streptococcus pneumoniae R6	64.854	94.342	0.612
comA	Streptococcus mitis SK321	64.714	94.342	0.611
comA	Streptococcus pneumoniae TIGR4	64.575	94.342	0.609
comA	Streptococcus gordonii str. Challis substr. CH1	64.435	94.342	0.608