Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   HBA50_RS03030 Genome accession   NZ_CP050133
Coordinates   590771..591472 (+) Length   233 a.a.
NCBI ID   WP_045501071.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 585771..596472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS03005 (HBA50_03005) - 586390..587238 (+) 849 WP_045501061.1 metallophosphoesterase family protein -
  HBA50_RS03010 (HBA50_03010) - 587296..587748 (+) 453 WP_002931101.1 Rrf2 family transcriptional regulator -
  HBA50_RS03015 (HBA50_03015) - 587975..588832 (+) 858 WP_045501065.1 VOC family protein -
  HBA50_RS03020 (HBA50_03020) - 588868..589374 (+) 507 WP_045501067.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  HBA50_RS03025 (HBA50_03025) - 589426..590508 (-) 1083 WP_045501069.1 Xaa-Pro peptidase family protein -
  HBA50_RS03030 (HBA50_03030) micA 590771..591472 (+) 702 WP_045501071.1 response regulator YycF Regulator
  HBA50_RS03035 (HBA50_03035) micB 591465..592829 (+) 1365 WP_005589490.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HBA50_RS03040 (HBA50_03040) vicX 592822..593622 (+) 801 WP_037586201.1 MBL fold metallo-hydrolase Regulator
  HBA50_RS03050 (HBA50_03050) - 593935..594294 (+) 360 WP_015605195.1 YbaN family protein -
  HBA50_RS03055 (HBA50_03055) rnc 594440..595129 (+) 690 WP_045501072.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26760.71 Da        Isoelectric Point: 4.8934

>NTDB_id=430207 HBA50_RS03030 WP_045501071.1 590771..591472(+) (micA) [Streptococcus cristatus ATCC 51100]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGKEALEMFEAEQPDILILDLMLPEVDGLDVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKALLRRSELVPDSHVDESSPKELFIGDLQILPDAFVVKKHGKELELTH
REFELLHHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYIRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=430207 HBA50_RS03030 WP_045501071.1 590771..591472(+) (micA) [Streptococcus cristatus ATCC 51100]
ATGAAAAAAATATTAGTTGTAGATGACGAGAAGCCAATCTCGGACATTATAAAGTTTAACATGGCTAAGGAAGGCTATGA
AGTACTGACAGCCTTTGATGGTAAGGAAGCTCTAGAAATGTTTGAAGCAGAGCAACCGGATATCTTGATTCTGGATTTGA
TGTTGCCAGAAGTGGATGGACTGGATGTTGCCCGGACCATTCGCAAGACCAGCAATGTGCCGATTATTGTACTTTCGGCC
AAAGATAGCGAGTTCGATAAGGTAATTGGTCTGGAGATCGGTGCCGATGACTATGTGACCAAGCCCTTTTCAAATCGTGA
ATTATTGGCTCGGGTCAAGGCCTTGTTGCGCCGTTCTGAACTAGTCCCAGATAGTCATGTGGATGAGAGCAGTCCAAAGG
AACTGTTTATTGGGGATTTGCAGATTCTTCCAGATGCTTTTGTGGTGAAAAAACATGGGAAAGAATTGGAATTAACCCAT
CGTGAATTTGAACTTTTGCACCATTTGGCGACTCATGTTGGTCAGGTCATGACGCGTGAGCATTTGCTAGAGACCGTCTG
GGGCTATGATTACTTTGGAGATGTGCGGACAGTCGATGTGACTATTCGCCGTCTGCGCGAAAAAATCGAAGATACTCCAA
GCCGTCCGGAGTATATCCTGACTCGCCGCGGTGTCGGTTATTACATAAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

100

0.82
  vicR Streptococcus mutans UA159

79.149

100

0.798
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

98.283

0.442
  covR Streptococcus salivarius strain HSISS4

42.795

98.283

0.421
  scnR Streptococcus mutans UA159

36.957

98.712

0.365