Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   HBA50_RS03035 Genome accession   NZ_CP050133
Coordinates   591465..592829 (+) Length   454 a.a.
NCBI ID   WP_005589490.1    Uniprot ID   A0A0F2CQ87
Organism   Streptococcus cristatus ATCC 51100     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 586465..597829
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS03010 (HBA50_03010) - 587296..587748 (+) 453 WP_002931101.1 Rrf2 family transcriptional regulator -
  HBA50_RS03015 (HBA50_03015) - 587975..588832 (+) 858 WP_045501065.1 VOC family protein -
  HBA50_RS03020 (HBA50_03020) - 588868..589374 (+) 507 WP_045501067.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  HBA50_RS03025 (HBA50_03025) - 589426..590508 (-) 1083 WP_045501069.1 Xaa-Pro peptidase family protein -
  HBA50_RS03030 (HBA50_03030) micA 590771..591472 (+) 702 WP_045501071.1 response regulator YycF Regulator
  HBA50_RS03035 (HBA50_03035) micB 591465..592829 (+) 1365 WP_005589490.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HBA50_RS03040 (HBA50_03040) vicX 592822..593622 (+) 801 WP_037586201.1 MBL fold metallo-hydrolase Regulator
  HBA50_RS03050 (HBA50_03050) - 593935..594294 (+) 360 WP_015605195.1 YbaN family protein -
  HBA50_RS03055 (HBA50_03055) rnc 594440..595129 (+) 690 WP_045501072.1 ribonuclease III -

Sequence

Protein


Download         Length: 454 a.a.        Molecular weight: 51573.53 Da        Isoelectric Point: 4.5101

>NTDB_id=430208 HBA50_RS03035 WP_005589490.1 591465..592829(+) (micB) [Streptococcus cristatus ATCC 51100]
MIETLKEFVLSPDFVFSLIVVGFIIVVALLLLENRRDTQKLVQLNQKIKGLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDDVLNTSILDLLDIADEYDLRELITKVPE
LTIDSQDENGEYVSLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPEFVKVSLTETNRMMRMVTDLLSLSRIDNNTSHLDVELTNFTAFITYILNRFDKIKNQDETKKYEIIRDYSITPIW
VEIDTDKMTQVIDNIMNNAIKYSPDGGTITVSVRTTDVQLILSISDEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDNDAVRVDDWENEENVESEHD

Nucleotide


Download         Length: 1365 bp        

>NTDB_id=430208 HBA50_RS03035 WP_005589490.1 591465..592829(+) (micB) [Streptococcus cristatus ATCC 51100]
ATGATTGAAACGCTAAAAGAATTCGTACTTTCTCCTGACTTTGTCTTTTCACTGATTGTTGTCGGCTTTATCATCGTCGT
GGCTCTTTTGCTACTGGAAAATCGACGAGATACTCAAAAGCTGGTGCAGTTAAACCAAAAGATCAAAGGATTGATTGCAG
GAGATTATTCAGAAGTTTTAGATATGCAGGGCAGTCCTGAAATCACGGACATGACCAATTCCATCAATGATCTCTCTGAA
GTCATCCGCCTGACGCATGAAAATTTGGAGCAAGAAACCAAGCGTCTATCCAGTATCCTGTCTTACATGACGGATGGCGT
GCTTGCGACCAATCGCCGAGGACAGATTATTACCATCAATGACATGGCAACCAAGCAATTGGGTGTCAAACGTGATGATG
TCCTTAATACCAGTATTTTAGATTTGCTGGATATTGCTGATGAGTATGATCTGCGCGAATTGATCACCAAGGTTCCAGAA
TTGACTATTGATTCTCAAGATGAAAATGGTGAATATGTAAGCCTGCGGGTTCGCTTCGCCTTGATCAGACGGGAGTCAGG
TTTTATATCAGGGTTGGTAGCAGTGCTACATGATACAACGGAGCAGGACAAGGAAGAGCGGGAGCGTCGGCTTTTCGTTT
CCAATGTTAGCCATGAATTGCGGACGCCTCTAACCAGTGTGAAATCCTATCTGGAAGCCTTGGATGATGGCGCTCTGTCA
GAGCCTGTTGCACCGGAATTTGTCAAGGTTTCACTAACCGAGACAAACCGTATGATGCGGATGGTGACGGACTTGCTTAG
CTTATCGCGGATTGATAATAATACCAGCCATCTGGATGTTGAGCTGACCAATTTTACAGCCTTTATCACCTATATCCTCA
ACCGTTTTGATAAGATAAAAAATCAGGATGAGACCAAAAAATATGAGATTATCAGGGATTATTCAATTACACCGATTTGG
GTAGAGATTGACACGGATAAGATGACCCAGGTGATTGATAATATCATGAACAATGCCATCAAGTATTCGCCTGATGGTGG
GACGATTACGGTTTCTGTGAGAACAACAGATGTTCAGTTGATTCTCTCGATTTCAGATGAAGGTCTGGGCATTCCCAAGC
AGGATCTGCCAAAGATTTTTGATCGTTTCTATCGGGTGGATAAGGCCCGCAGTCGAGCCCAGGGAGGAACGGGCTTGGGT
CTGGCTATTGCTAAAGAAATTATCAAGCAGCATCATGGCTTTATTTGGGCCAAGAGTGAGTATGGCAAAGGATCTACCTT
TACCATTGTTCTTCCATATGATAACGATGCTGTCCGTGTAGATGACTGGGAAAATGAAGAGAATGTAGAAAGTGAACATG
ACTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2CQ87

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

96.696

0.76
  vicK Streptococcus mutans UA159

71.642

88.546

0.634