Detailed information NTG0427888

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: G7052_RS06980
• Genome accession: NZ_CP049799
• Coordinates: 1423532..1424368 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1040
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1418532..1429368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G7052_RS06950 (G7052_06950)	-	1419086..1419454 (+)	369	WP_010922310.1	hypothetical protein	-
G7052_RS06955 (G7052_06955)	-	1419504..1420415 (-)	912	WP_136273951.1	diacylglycerol kinase family protein	-
G7052_RS06960 (G7052_06960)	-	1420532..1421182 (-)	651	WP_002984629.1	hemolysin III family protein	-
G7052_RS06965 (G7052_06965)	-	1421179..1421619 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
G7052_RS06970 (G7052_06970)	ylqF	1421838..1422686 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
G7052_RS06975 (G7052_06975)	-	1422676..1423467 (+)	792	WP_011285534.1	ribonuclease HII	-
G7052_RS06980 (G7052_06980)	dprA	1423532..1424368 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
G7052_RS06985 (G7052_06985)	topA	1424475..1426604 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
G7052_RS06990 (G7052_06990)	-	1426679..1427561 (-)	883	Protein_1301	LysR family transcriptional regulator	-
G7052_RS06995 (G7052_06995)	-	1427574..1428119 (+)	546	Protein_1302	PTS sugar transporter subunit IIC	-
G7052_RS07000 (G7052_07000)	-	1428134..1429126 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=427888 G7052_RS06980 WP_010922314.1 1423532..1424368(+) (dprA) [Streptococcus pyogenes strain 1040]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=427888 G7052_RS06980 WP_010922314.1 1423532..1424368(+) (dprA) [Streptococcus pyogenes strain 1040]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367