Detailed information NTG0425291

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: G6Z52_RS04380
• Genome accession: NZ_CP049187
• Coordinates: 877130..877966 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1687
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 872130..882966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G6Z52_RS04350 (G6Z52_04375)	-	872612..873052 (+)	441	WP_002989779.1	hypothetical protein	-
G6Z52_RS04355 (G6Z52_04380)	-	873102..874013 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
G6Z52_RS04360 (G6Z52_04385)	-	874130..874780 (-)	651	WP_002984629.1	hemolysin III family protein	-
G6Z52_RS04365 (G6Z52_04390)	-	874777..875217 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
G6Z52_RS04370 (G6Z52_04395)	ylqF	875436..876284 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
G6Z52_RS04375 (G6Z52_04400)	-	876274..877065 (+)	792	WP_002989771.1	ribonuclease HII	-
G6Z52_RS04380 (G6Z52_04405)	dprA	877130..877966 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
G6Z52_RS04385 (G6Z52_04410)	topA	878073..880202 (+)	2130	WP_002989768.1	type I DNA topoisomerase	-
G6Z52_RS04390 (G6Z52_04415)	-	880277..881134 (-)	858	Protein_813	LysR family transcriptional regulator	-
G6Z52_RS04395 (G6Z52_04420)	-	881174..881740 (+)	567	Protein_814	PTS sugar transporter subunit IIC	-
G6Z52_RS04400 (G6Z52_04425)	-	881755..882747 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=425291 G6Z52_RS04380 WP_002989770.1 877130..877966(+) (dprA) [Streptococcus pyogenes strain TSPY1687]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=425291 G6Z52_RS04380 WP_002989770.1 877130..877966(+) (dprA) [Streptococcus pyogenes strain TSPY1687]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367