Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   G5C59_RS05045 Genome accession   NZ_CP049088
Coordinates   1040763..1042025 (-) Length   420 a.a.
NCBI ID   WP_021113424.1    Uniprot ID   A0A836Z0A6
Organism   Glaesserella parasuis strain sHPS7     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1035763..1047025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G5C59_RS11870 - 1036387..1036659 (-) 273 WP_021118737.1 hypothetical protein -
  G5C59_RS11875 - 1036687..1037241 (-) 555 WP_420370899.1 IS256 family transposase, variant Zn-binding type -
  G5C59_RS05020 (G5C59_04990) trxA 1037579..1037893 (-) 315 WP_015940165.1 thioredoxin -
  G5C59_RS05025 (G5C59_04995) - 1038190..1038819 (-) 630 WP_005712495.1 LysE family transporter -
  G5C59_RS05030 (G5C59_05000) - 1038821..1039291 (-) 471 WP_021118735.1 phosphatidylglycerophosphatase A -
  G5C59_RS05035 (G5C59_05005) thiL 1039294..1040262 (-) 969 WP_021113430.1 thiamine-phosphate kinase -
  G5C59_RS05040 (G5C59_05010) nusB 1040271..1040684 (-) 414 WP_021112072.1 transcription antitermination factor NusB -
  G5C59_RS05045 (G5C59_05015) comE 1040763..1042025 (-) 1263 WP_021113424.1 type IV pilus secretin PilQ Machinery gene
  G5C59_RS05050 (G5C59_05020) comD 1042035..1042421 (-) 387 WP_021112070.1 hypothetical protein Machinery gene
  G5C59_RS05055 (G5C59_05025) comC 1042421..1042951 (-) 531 WP_021113425.1 hypothetical protein Machinery gene
  G5C59_RS05060 (G5C59_05030) comB 1042948..1043469 (-) 522 WP_021113427.1 hypothetical protein Machinery gene
  G5C59_RS05065 (G5C59_05035) comA 1043445..1044122 (-) 678 WP_021113429.1 hypothetical protein Machinery gene
  G5C59_RS05070 (G5C59_05040) - 1044276..1046831 (+) 2556 WP_021119495.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46971.81 Da        Isoelectric Point: 7.3676

>NTDB_id=424621 G5C59_RS05045 WP_021113424.1 1040763..1042025(-) (comE) [Glaesserella parasuis strain sHPS7]
MRYLFLLFFATFPVLANQQISLSIRNAPTAEIISYLAEETGKNITISDEIKDTKNFRVEKSHFDEILNSLIKTHQLNLKK
ENGIYYIHQAQEHKQHTTAQLVNALPKLITKTIKLHYSKASEVIESLTKGQGNLLSESGYLHFDDRSNSIIVKDSAASVK
NFTQLIESLDKPTEQIAIEARIVTISSEHLQQLGVRWGLFSPNENHYKLAGNLEGNGLTTNNLNVNFPVNPSASVALQIA
AINSRVLDLELTALESENNIEIIASPRLLTTDKKTASIKQGTEIPYAMYSKKEEITDIEFREAVLGLEVTPHISKQNQIL
LDLAISQNSPNNQINNTMVTIDKQEIKTQVLAKHGETIVLGGIFQHLIAKGEDKVPLLGSIPVIKRLFSQSQDKISKREL
VIFVTPYIVKSEKIGAEKQK

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=424621 G5C59_RS05045 WP_021113424.1 1040763..1042025(-) (comE) [Glaesserella parasuis strain sHPS7]
ATGCGTTATTTATTTCTGCTCTTCTTTGCTACTTTTCCTGTATTAGCAAACCAACAAATTTCACTTTCGATAAGAAATGC
CCCAACGGCAGAGATTATTAGTTATTTGGCGGAGGAAACGGGAAAGAATATTACAATTTCGGATGAAATTAAAGATACAA
AAAATTTCAGAGTAGAAAAAAGCCATTTTGATGAGATATTAAATAGTTTAATCAAAACACATCAATTAAATTTAAAAAAA
GAAAATGGCATTTACTATATTCATCAAGCCCAAGAACATAAACAACATACTACGGCACAATTAGTTAATGCTCTGCCTAA
ATTAATCACCAAAACAATCAAGTTACACTATTCCAAAGCCTCTGAAGTTATAGAGTCTTTAACAAAAGGGCAAGGCAATT
TACTATCAGAAAGTGGTTATCTTCACTTTGATGATCGCAGTAATAGCATTATCGTCAAAGACAGTGCCGCCTCAGTTAAA
AACTTTACTCAACTTATCGAAAGCCTAGATAAACCAACGGAACAAATTGCAATTGAAGCCCGAATTGTCACTATCAGCAG
TGAACATTTACAACAACTTGGCGTGCGTTGGGGCTTATTTTCCCCTAACGAAAATCACTACAAATTGGCAGGCAATTTAG
AAGGCAACGGATTAACTACCAACAACTTAAACGTAAATTTTCCAGTAAACCCGTCCGCTTCTGTTGCCTTACAAATTGCT
GCAATCAACAGCCGTGTACTTGATTTAGAACTTACTGCATTAGAAAGCGAAAATAACATAGAGATCATTGCAAGCCCTCG
CTTACTCACAACAGATAAAAAAACAGCGAGTATCAAACAAGGTACAGAAATTCCTTATGCAATGTACAGTAAGAAAGAGG
AAATCACCGATATTGAATTTCGTGAAGCCGTTTTGGGGTTAGAGGTCACGCCACATATTTCTAAACAAAATCAGATTTTG
TTAGACCTCGCTATCAGCCAAAATTCGCCCAATAACCAAATAAATAATACAATGGTGACAATTGATAAACAGGAAATCAA
AACGCAAGTTCTAGCTAAACACGGTGAAACCATCGTATTAGGCGGTATTTTTCAACATCTGATCGCCAAAGGCGAAGATA
AAGTACCGCTGTTAGGCAGTATCCCCGTGATTAAACGCTTATTTAGCCAAAGCCAAGATAAAATCTCTAAACGAGAATTA
GTGATTTTTGTCACGCCTTATATTGTGAAATCTGAAAAAATAGGAGCGGAAAAGCAGAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(253-410)

Bacterial type II/III secretion system short domain (Secretin_N)

(110-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A836Z0A6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

100

100

1
  comE Haemophilus influenzae Rd KW20

52.941

100

0.536
  comE Haemophilus influenzae 86-028NP

52

100

0.526
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

37.923

98.571

0.374
  pilQ Vibrio cholerae strain A1552

37.923

98.571

0.374
  pilQ Vibrio campbellii strain DS40M4

36.967

100

0.371