Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   PARA_RS00545 Genome accession   NC_015964
Coordinates   104741..105964 (+) Length   407 a.a.
NCBI ID   WP_014064062.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae T3T1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99741..110964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PARA_RS00520 (PARA_01050) - 100325..101119 (-) 795 WP_014064057.1 sulfite exporter TauE/SafE family protein -
  PARA_RS00525 (PARA_01060) rppH 101119..101712 (-) 594 WP_014064058.1 RNA pyrophosphohydrolase -
  PARA_RS00530 (PARA_01070) ampD 102197..102760 (-) 564 WP_014064059.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  PARA_RS00535 (PARA_01080) pilA 102903..103346 (+) 444 WP_014064060.1 prepilin peptidase-dependent pilin Machinery gene
  PARA_RS00540 (PARA_01090) pilB 103353..104732 (+) 1380 WP_014064061.1 GspE/PulE family protein Machinery gene
  PARA_RS00545 (PARA_01100) pilC 104741..105964 (+) 1224 WP_014064062.1 type II secretion system F family protein Machinery gene
  PARA_RS00550 (PARA_01110) pilD 105961..106638 (+) 678 WP_014064063.1 prepilin peptidase Machinery gene
  PARA_RS00555 (PARA_01120) coaE 106727..107347 (+) 621 WP_014064064.1 dephospho-CoA kinase -
  PARA_RS00560 (PARA_01130) yacG 107340..107546 (+) 207 WP_005695505.1 DNA gyrase inhibitor YacG -
  PARA_RS00565 (PARA_01140) - 107543..107824 (+) 282 WP_014064065.1 GNAT family N-acetyltransferase -
  PARA_RS00570 (PARA_01150) rhlB 107914..109173 (+) 1260 WP_014064066.1 ATP-dependent RNA helicase RhlB -
  PARA_RS00575 (PARA_01160) mreD 109214..109702 (-) 489 WP_014064067.1 rod shape-determining protein MreD -
  PARA_RS00580 (PARA_01170) mreC 109702..110766 (-) 1065 WP_014064068.1 rod shape-determining protein MreC -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 46229.88 Da        Isoelectric Point: 9.7421

>NTDB_id=42226 PARA_RS00545 WP_014064062.1 104741..105964(+) (pilC) [Haemophilus parainfluenzae T3T1]
MAKQKLFYFQAYDQRQQWQKGSLVAQSKQAAQFQLIAKGFSHIRLQQDWQLNQKPKNAEISALLNQLATLLSSAIPLKNA
LHILQDNCTQLGLHQWLGALIELIESGLPFSQSLEIQGKYLNFQEIQLIQVGEMTGKLAEVCTKIAERRTQSLTLQRKLQ
KIMLYPAMVLGISLSLTLILLLFVVPQFAEMYGENSAELPTLTAVLLAMSQFLQLHFIALMIVCIFAIFMLKMALKHSLW
LNQKKNALVNRMPIWGNIICLSRLISFSHNLQLMLQSGVALTPALNSFLPKQQTWQIQRTLKGDILLQQEVRSILQWVSQ
GYPFSESVSSHLFPMEAQQMLQIGEKSGKLALMLRHIADNYQEKLNHQIDLLSQLLEPLMMLIIGSLIGIIMMGMYLPIF
NMGSVIQ

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=42226 PARA_RS00545 WP_014064062.1 104741..105964(+) (pilC) [Haemophilus parainfluenzae T3T1]
ATGGCAAAGCAAAAACTCTTTTATTTTCAAGCCTATGATCAGCGACAACAATGGCAAAAAGGCAGTCTGGTTGCCCAATC
TAAACAAGCTGCACAATTCCAGTTAATCGCAAAAGGTTTTAGCCACATTCGCTTGCAACAAGATTGGCAACTGAATCAGA
AACCTAAAAATGCTGAGATCAGTGCTTTATTAAATCAGCTAGCTACACTACTCAGCTCTGCCATTCCATTAAAAAATGCA
TTGCACATTTTGCAAGATAACTGCACGCAATTGGGATTGCATCAGTGGCTTGGCGCCTTAATTGAGTTAATTGAAAGTGG
TCTTCCGTTTTCACAAAGCTTAGAAATACAAGGAAAGTATTTAAATTTTCAAGAAATTCAGCTCATTCAGGTGGGAGAAA
TGACAGGAAAACTGGCAGAGGTATGCACTAAAATTGCCGAACGTCGGACACAATCATTAACGCTTCAACGCAAATTGCAA
AAAATTATGCTTTATCCAGCCATGGTATTAGGTATTTCGCTGTCACTTACGTTGATTTTACTACTTTTCGTTGTACCACA
ATTTGCTGAAATGTATGGCGAAAACTCAGCTGAGCTGCCTACATTGACTGCTGTGTTATTAGCCATGTCTCAATTCCTAC
AACTTCATTTTATCGCGTTGATGATTGTCTGTATTTTCGCTATTTTTATGCTGAAGATGGCATTAAAACATTCTCTTTGG
CTAAATCAAAAAAAGAATGCGCTGGTTAATCGTATGCCGATTTGGGGCAATATCATTTGCCTTTCTCGTTTAATTAGTTT
TAGCCATAACCTGCAATTAATGCTTCAATCCGGTGTGGCATTAACGCCGGCCTTAAATAGCTTCCTCCCCAAACAACAAA
CCTGGCAAATACAACGTACCTTAAAAGGTGATATTCTGCTACAACAAGAAGTGCGGTCAATTTTACAGTGGGTTTCTCAA
GGTTATCCATTTTCAGAAAGCGTCAGTAGTCATCTTTTTCCAATGGAAGCACAACAAATGCTACAGATTGGAGAGAAAAG
TGGAAAACTTGCGTTGATGTTGCGTCATATTGCTGATAACTATCAAGAAAAACTCAATCATCAAATTGATTTACTTTCCC
AACTTTTAGAGCCTTTAATGATGCTCATCATTGGTAGTTTAATAGGTATCATAATGATGGGCATGTATCTGCCAATTTTT
AATATGGGTTCGGTAATCCAGTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-398)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae Rd KW20

69.307

99.263

0.688
  pilC Haemophilus influenzae 86-028NP

68.564

99.263

0.681
  pilC Glaesserella parasuis strain SC1401

39.401

98.526

0.388

Multiple sequence alignment