Detailed information NTG0042001

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SPPN_RS06180
• Genome accession: NC_015875
• Coordinates: 1192872..1193720 (-)
• Length: 282 a.a.
• NCBI ID: WP_000705319.1
• Uniprot ID: -
• Organism: Streptococcus pseudopneumoniae IS7493
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1187872..1198720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPPN_RS06155 (SPPN_06220)	-	1188143..1188502 (-)	360	WP_001237210.1	YbaN family protein	-
SPPN_RS13930 (SPPN_06225)	-	1188515..1188661 (-)	147	WP_000693333.1	hypothetical protein	-
SPPN_RS06165 (SPPN_06230)	topA	1188759..1190846 (-)	2088	WP_000179654.1	type I DNA topoisomerase	-
SPPN_RS06170 (SPPN_06235)	-	1191012..1192055 (-)	1044	WP_014017268.1	TIGR00341 family protein	-
SPPN_RS13935 (SPPN_06240)	-	1192124..1192276 (-)	153	WP_014017269.1	hypothetical protein	-
SPPN_RS06180 (SPPN_06250)	dprA/cilB/dalA	1192872..1193720 (-)	849	WP_000705319.1	DNA-processing protein DprA	Machinery gene
SPPN_RS06185 (SPPN_06255)	-	1193931..1196438 (-)	2508	WP_148255718.1	DUF1542 domain-containing protein	-
SPPN_RS06190 (SPPN_06260)	-	1196671..1196889 (-)	219	WP_014017271.1	YSIRK-type signal peptide-containing protein	-
SPPN_RS06195 (SPPN_06265)	-	1196909..1197655 (-)	747	WP_000458340.1	N-acetylmuramoyl-L-alanine amidase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31066.76 Da
• Isoelectric Point: 5.6729

>NTDB_id=42001 SPPN_RS06180 WP_000705319.1 1192872..1193720(-) (dprA/cilB/dalA) [Streptococcus pseudopneumoniae IS7493]
MKITNYEIYKLKKSGLTNQQVLKVLEYGENFDQELLLGDIADISGCRNPAVFMERYFQIDDAHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEG
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGKDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=42001 SPPN_RS06180 WP_000705319.1 1192872..1193720(-) (dprA/cilB/dalA) [Streptococcus pseudopneumoniae IS7493]
ATGAAAATCACAAACTATGAAATCTATAAGTTGAAAAAATCAGGTTTGACCAATCAACAGGTTTTGAAGGTCCTAGAATA
TGGCGAAAATTTCGATCAAGAACTGTTGTTAGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGGAGAAGGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGACGACTGT
TATCCTTGGGATTTGAGTGAAATATACGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCTTGAAATTCCC
GAAGGTAGCGGTTGTGGGTAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAGGGCTTGGAAA
ATGAACTAGTTATCGTCAGTGGATTAGCCAAGGGGATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGGACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTTAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGCGTGATTGTAGCAGAGGCCAAGATGCGCTCAGGTAGTCTTATTACCTGTGAGAGAGCAATGGAAGGA
GGGCGTGATGTTTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATCCAAGAAGGAGC
AAAATTGGTCACAAGTGGGAAGGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	98.227	100	0.982
dprA/cilB/dalA	Streptococcus pneumoniae D39	98.227	100	0.982
dprA/cilB/dalA	Streptococcus pneumoniae R6	98.227	100	0.982
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	96.809	100	0.968
dprA	Streptococcus mutans UA159	62.5	99.291	0.621
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Haemophilus influenzae Rd KW20	38.577	94.681	0.365