Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SPPN_RS05870 Genome accession   NC_015875
Coordinates   1133293..1133997 (-) Length   234 a.a.
NCBI ID   WP_000722069.1    Uniprot ID   -
Organism   Streptococcus pseudopneumoniae IS7493     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1128293..1138997
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS05845 (SPPN_05920) - 1128604..1130475 (-) 1872 WP_000963214.1 Eco57I restriction-modification methylase domain-containing protein -
  SPPN_RS05850 (SPPN_05925) - 1130551..1130805 (-) 255 WP_014017264.1 type II toxin-antitoxin system RelE family toxin -
  SPPN_RS05855 (SPPN_05930) relB 1130807..1131049 (-) 243 WP_000208079.1 type II toxin-antitoxin system RelB family antitoxin -
  SPPN_RS05860 (SPPN_05935) vicX 1131140..1131949 (-) 810 WP_001289495.1 MBL fold metallo-hydrolase Regulator
  SPPN_RS05865 (SPPN_05940) micB 1131951..1133300 (-) 1350 WP_000886221.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SPPN_RS05870 (SPPN_05945) micA 1133293..1133997 (-) 705 WP_000722069.1 response regulator YycF Regulator
  SPPN_RS05875 (SPPN_05950) mutY 1134053..1135228 (-) 1176 WP_000886139.1 A/G-specific adenine glycosylase -
  SPPN_RS13190 - 1135274..1135444 (-) 171 WP_158083587.1 hypothetical protein -
  SPPN_RS05885 (SPPN_05955) - 1135644..1137314 (-) 1671 WP_000845266.1 formate--tetrahydrofolate ligase -
  SPPN_RS05890 (SPPN_05960) coaB 1137540..1138229 (+) 690 WP_000699528.1 phosphopantothenate--cysteine ligase -
  SPPN_RS05895 (SPPN_05965) coaC 1138241..1138792 (+) 552 WP_001284126.1 phosphopantothenoylcysteine decarboxylase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26799.63 Da        Isoelectric Point: 4.7209

>NTDB_id=42000 SPPN_RS05870 WP_000722069.1 1133293..1133997(-) (micA) [Streptococcus pseudopneumoniae IS7493]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEAESKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHAGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

Nucleotide


Download         Length: 705 bp        

>NTDB_id=42000 SPPN_RS05870 WP_000722069.1 1133293..1133997(-) (micA) [Streptococcus pseudopneumoniae IS7493]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATCAAGTTTAATATGACCAAGGAAGGGTACGA
GGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTTTGGATTTGA
TGCTTCCAGAAATTGATGGCTTAGAAGTTGCGAAGACTATTCGGAAGACTAGTAGTGTGCCTATTATCATGCTGTCAGCT
AAGGATAGCGAATTTGATAAGGTTATCGGTTTAGAGCTTGGTGCAGATGACTATGTAACCAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGGCAGGAAGCAGAAAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGAGAAGAACTAGACTTAACC
CACCGTGAGTTTGAGCTTTTGTATCATTTGGCATCGCATGCAGGTCAAGTCATTACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACGGTTGATGTGACTGTCCGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

98.718

100

0.987
  vicR Streptococcus mutans UA159

78.541

99.573

0.782
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.348

98.291

0.436
  covR Streptococcus salivarius strain HSISS4

44.156

98.718

0.436

Multiple sequence alignment