Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   SPPN_RS05865 Genome accession   NC_015875
Coordinates   1131951..1133300 (-) Length   449 a.a.
NCBI ID   WP_000886221.1    Uniprot ID   A0A1S9ZK37
Organism   Streptococcus pseudopneumoniae IS7493     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1126951..1138300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS05840 (SPPN_05915) - 1127544..1128494 (-) 951 WP_000658131.1 Abi family protein -
  SPPN_RS05845 (SPPN_05920) - 1128604..1130475 (-) 1872 WP_000963214.1 Eco57I restriction-modification methylase domain-containing protein -
  SPPN_RS05850 (SPPN_05925) - 1130551..1130805 (-) 255 WP_014017264.1 type II toxin-antitoxin system RelE family toxin -
  SPPN_RS05855 (SPPN_05930) relB 1130807..1131049 (-) 243 WP_000208079.1 type II toxin-antitoxin system RelB family antitoxin -
  SPPN_RS05860 (SPPN_05935) vicX 1131140..1131949 (-) 810 WP_001289495.1 MBL fold metallo-hydrolase Regulator
  SPPN_RS05865 (SPPN_05940) micB 1131951..1133300 (-) 1350 WP_000886221.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SPPN_RS05870 (SPPN_05945) micA 1133293..1133997 (-) 705 WP_000722069.1 response regulator YycF Regulator
  SPPN_RS05875 (SPPN_05950) mutY 1134053..1135228 (-) 1176 WP_000886139.1 A/G-specific adenine glycosylase -
  SPPN_RS13190 - 1135274..1135444 (-) 171 WP_158083587.1 hypothetical protein -
  SPPN_RS05885 (SPPN_05955) - 1135644..1137314 (-) 1671 WP_000845266.1 formate--tetrahydrofolate ligase -
  SPPN_RS05890 (SPPN_05960) coaB 1137540..1138229 (+) 690 WP_000699528.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51704.35 Da        Isoelectric Point: 4.8585

>NTDB_id=41999 SPPN_RS05865 WP_000886221.1 1131951..1133300(-) (micB) [Streptococcus pseudopneumoniae IS7493]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIRLKQVNQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVQEDVLNRSILEVLKIEEDYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDQGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=41999 SPPN_RS05865 WP_000886221.1 1131951..1133300(-) (micB) [Streptococcus pseudopneumoniae IS7493]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATTCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAGAATAGACGTGATAATATTCGATTGAAGCAAGTCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAAAGTAAGCGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
CCTTGCGACCAATCGTCGGGGGCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTCAGGAAGATG
TTCTGAATAGAAGCATTTTGGAAGTACTCAAGATAGAAGAAGACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGGAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTTTAACCAGCGTGAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTGTCTCTGGACGAAACCAACCGTATGATGCGCATGGTGACGGACCTCCTTCA
TCTTTCACGGATTGATAATGCCACCAGTCACTTGGATGTGGAACTGATTAACTTTACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACACAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCAGGGTTTAGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATAAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATATGGCAAGGGTTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGACGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(98-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S9ZK37

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

98.441

100

0.984
  vicK Streptococcus mutans UA159

69.9

89.532

0.626

Multiple sequence alignment