Detailed information NTG0041856

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SALIVB_RS10330
• Genome accession: NC_015760
• Coordinates: 2214982..2216217 (+)
• Length: 411 a.a.
• NCBI ID: WP_013991347.1
• Uniprot ID: A0AB37CMH1
• Organism: Streptococcus salivarius CCHSS3
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2209982..2221217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVB_RS10300 (SALIVB_2149)	tnpA	2212431..2212895 (-)	465	WP_002883780.1	IS200/IS605 family transposase	-
SALIVB_RS10320 (SALIVB_2153)	-	2213598..2214281 (-)	684	WP_013991345.1	YoaK family protein	-
SALIVB_RS10325 (SALIVB_2154)	rlmH	2214297..2214776 (-)	480	WP_014632473.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SALIVB_RS10330 (SALIVB_2155)	htrA	2214982..2216217 (+)	1236	WP_013991347.1	S1C family serine protease	Regulator
SALIVB_RS10335 (SALIVB_2156)	spo0J	2216283..2217050 (+)	768	WP_013991348.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.09 Da
• Isoelectric Point: 4.6266

>NTDB_id=41856 SALIVB_RS10330 WP_013991347.1 2214982..2216217(+) (htrA) [Streptococcus salivarius CCHSS3]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNSTDTGVKTAKTVYNNTTDTTKAVKKVQNAVVSVINYQEGS
SSDSLNELYGRIFGGDDSSDSSQDKSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKIKTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTVTMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISMADLNSLS
SSATSKLDLPDDVKAGVVVGSVQKGMPADGKLQENDVITEIDGKEISSKTDIQTNLYSHSIGDTIKVTFYRGKEKKTEEL
KLTKSTEDLSD

Nucleotide

• Length: 1236 bp

>NTDB_id=41856 SALIVB_RS10330 WP_013991347.1 2214982..2216217(+) (htrA) [Streptococcus salivarius CCHSS3]
GTGAAAAAATTTAACTGGAAAAAAATAGTAGCGCCAATTGCAATGCTTGTTATTGGCTTGCTCGGTGGTTTGCTAGGTGC
CTTTATCCTACTAACAGCAGCAGGGGTATCTTTTACCAATTCAACAGATACAGGTGTTAAAACAGCTAAGACCGTATACA
ATAATACAACAGATACAACTAAAGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTACCAAGAAGGGTCA
TCTTCAGATTCTCTAAATGAACTTTATGGCCGTATCTTTGGTGGAGATGATAGTTCTGACTCTAGCCAAGACAAATCAAA
AGATTCTGATGGGTTACAAGTCGCTGGTGAAGGTTCCGGTGTTATCTACAAAAAGGATGGTAAAGAGGCTTATATCGTAA
CCAACAACCACGTTGTCGATGGCGCTAAAAAACTTGAAATCATGCTTTCAGATGGATCAAAAATTACTGGTGAACTCGTT
GGTAAAGATACTTACTCTGACCTAGCAGTTGTCAAAGTTTCTTCAGATAAAATTAAAACCGTAGCGGAATTTGCAGACTC
AAACTCTCTCACAGTCGGTGAGAAGGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAGG
GAATCGTTTCTAGCCTTAGCCGTACCGTAACTATGCAAAACGACAATGGTGAAACTGTTTCAACAAATGCTATCCAAACA
GATGCTGCCATTAACCCTGGTAACTCAGGTGGTGCCTTAGTCAATATCGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCAGCAGTCGCTGGTAGCGCCGTTGAAGGTATGGGATTTGCCATTCCATCAAACGATGTTGTCGAAA
TCATCAATCAATTGGAAAAAGACGGTAAAGTTACACGACCAGCCCTAGGAATCTCAATGGCCGATCTTAACAGCCTTTCT
AGCAGTGCAACTTCTAAATTAGATTTACCAGATGATGTGAAAGCTGGAGTTGTAGTCGGCAGCGTTCAAAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAAAATGATGTTATCACTGAAATTGACGGTAAGGAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACAATCAAGGTAACCTTCTATCGTGGTAAAGAGAAGAAAACTGAAGAACTT
AAATTAACAAAATCTACAGAAGACTTGTCTGACTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (7-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus pneumoniae Rx1	54.279	99.513	0.54
htrA	Streptococcus pneumoniae R6	54.279	99.513	0.54
htrA	Streptococcus pneumoniae TIGR4	54.279	99.513	0.54
htrA	Streptococcus pneumoniae D39	54.279	99.513	0.54
htrA	Streptococcus mitis NCTC 12261	54.279	99.513	0.54