Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   M594_RS09855 Genome accession   NZ_CP047883
Coordinates   2053786..2054448 (-) Length   220 a.a.
NCBI ID   WP_173876701.1    Uniprot ID   A0A6M9FCX6
Organism   Streptococcus mitis strain S022-V3-A4     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2048786..2059448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS09830 (M594_09875) - 2048936..2049202 (-) 267 WP_001278168.1 Veg family protein -
  M594_RS09835 (M594_09880) dnaB 2049204..2050556 (-) 1353 WP_173876699.1 replicative DNA helicase -
  M594_RS09840 (M594_09885) rplI 2050600..2051052 (-) 453 WP_000864214.1 50S ribosomal protein L9 -
  M594_RS09845 (M594_09890) - 2051049..2053022 (-) 1974 WP_173876700.1 DHH family phosphoesterase -
  M594_RS09850 (M594_09895) hpf 2053158..2053706 (-) 549 WP_004255322.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  M594_RS09855 (M594_09900) comFC/cflB 2053786..2054448 (-) 663 WP_173876701.1 ComF family protein Machinery gene
  M594_RS09860 (M594_09905) comFA/cflA 2054445..2055743 (-) 1299 WP_173876702.1 DEAD/DEAH box helicase Machinery gene
  M594_RS09865 (M594_09910) - 2055800..2056435 (+) 636 WP_173876703.1 YigZ family protein -
  M594_RS09870 (M594_09915) - 2056451..2056894 (+) 444 WP_173876704.1 PH domain-containing protein -
  M594_RS09875 (M594_09920) cysK 2056991..2057917 (+) 927 WP_173876705.1 cysteine synthase A -
  M594_RS09880 (M594_09925) tsf 2058039..2059079 (-) 1041 WP_173876706.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25254.27 Da        Isoelectric Point: 7.7129

>NTDB_id=418287 M594_RS09855 WP_173876701.1 2053786..2054448(-) (comFC/cflB) [Streptococcus mitis strain S022-V3-A4]
MKCLLCGQTMKAVLTFSSLLLLRNGVSCLCLDCDSTFEKIGEEYCPNCMKTGLSTKCQDCQFWCQEGIEVSHRGIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPERLLERGFNQVEGLVEAAGFSFQDLLEKREERASSS
KNRSERLGTELPFFIKRGVTIPKKILLIDDIYTTGTTINRVKKLLEEAGTEDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=418287 M594_RS09855 WP_173876701.1 2053786..2054448(-) (comFC/cflB) [Streptococcus mitis strain S022-V3-A4]
ATGAAGTGTTTGTTATGTGGGCAGACTATGAAGGCTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGGTGTCTC
CTGTCTTTGTTTAGATTGTGATTCTACTTTTGAGAAAATTGGAGAAGAGTACTGTCCAAACTGTATGAAAACAGGGTTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTCAAGAAGGAATTGAGGTCAGTCATAGAGGGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTTTTAAGAAAAGTTTTTGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTCGTAATTCCCCTAAGTCCTGAAAGATTACTTGAGAGGGGATTTAACC
AGGTTGAAGGTTTAGTTGAAGCAGCAGGGTTCTCTTTTCAAGACTTACTAGAGAAGAGAGAAGAGCGGGCCAGTTCTTCT
AAAAATCGTTCAGAACGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGGGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGACATTTACACTACTGGAACAACTATAAATCGTGTGAAGAAACTGTTGGAAGAGGCTGGTACTGAAGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(181-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M9FCX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

94.091

100

0.941
  comFC/cflB Streptococcus mitis NCTC 12261

90.455

100

0.905
  comFC/cflB Streptococcus pneumoniae TIGR4

90

100

0.9
  comFC/cflB Streptococcus pneumoniae Rx1

89.545

100

0.895
  comFC/cflB Streptococcus pneumoniae D39

89.545

100

0.895
  comFC/cflB Streptococcus pneumoniae R6

89.545

100

0.895
  comFC Bacillus subtilis subsp. subtilis str. 168

35.526

100

0.368

Multiple sequence alignment