Detailed information NTG0417655

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3S83_RS09860
• Genome accession: NZ_CP047843
• Coordinates: 1987621..1988664 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UP_620
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1982621..1993664

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S83_RS09830 (E3S83_09830)	-	1983043..1984299 (-)	1257	WP_072419726.1	aminopeptidase	-
E3S83_RS09835 (E3S83_09835)	-	1984302..1984502 (-)	201	WP_000180460.1	DUF1128 family protein	-
E3S83_RS09840 (E3S83_09840)	-	1984649..1985113 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
E3S83_RS09845 (E3S83_09845)	-	1985120..1985395 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E3S83_RS09850 (E3S83_09850)	-	1985673..1986890 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
E3S83_RS09855 (E3S83_09855)	vraR	1987002..1987631 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
E3S83_RS09860 (E3S83_09860)	vraS	1987621..1988664 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3S83_RS09865 (E3S83_09865)	liaF	1988661..1989362 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
E3S83_RS09870 (E3S83_09870)	-	1989377..1989763 (-)	387	WP_001110179.1	hypothetical protein	-
E3S83_RS09875 (E3S83_09875)	map	1989980..1990738 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
E3S83_RS09880 (E3S83_09880)	-	1991269..1992255 (+)	987	WP_000999713.1	FUSC family protein	-
E3S83_RS09885 (E3S83_09885)	-	1992745..1993158 (-)	414	WP_001566709.1	hypothetical protein	-
E3S83_RS09890 (E3S83_09890)	-	1993187..1993297 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=417655 E3S83_RS09860 WP_001017131.1 1987621..1988664(-) (vraS) [Staphylococcus aureus strain UP_620]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=417655 E3S83_RS09860 WP_001017131.1 1987621..1988664(-) (vraS) [Staphylococcus aureus strain UP_620]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1