Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   H8S71_RS20060 Genome accession   NZ_CP060417
Coordinates   3942291..3943493 (-) Length   400 a.a.
NCBI ID   WP_015250812.1    Uniprot ID   A0ABU0V6N7
Organism   Bacillus subtilis subsp. subtilis strain ONU 559     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3937291..3948493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H8S71_RS20035 (H8S71_20030) rocE 3937526..3938929 (-) 1404 WP_187001996.1 amino acid permease -
  H8S71_RS20040 (H8S71_20035) rocD 3939152..3940357 (-) 1206 WP_187001997.1 ornithine aminotransferase -
  H8S71_RS20045 (H8S71_20040) rocR 3940597..3941982 (+) 1386 WP_077670828.1 arginine utilization regulatory protein RocR -
  H8S71_RS20050 (H8S71_20045) - 3941964..3942131 (-) 168 Protein_3922 ATP-binding protein -
  H8S71_RS20055 (H8S71_20050) - 3942141..3942271 (-) 131 Protein_3923 hypothetical protein -
  H8S71_RS20060 (H8S71_20055) htrA 3942291..3943493 (-) 1203 WP_015250812.1 serine protease HtrC Regulator
  H8S71_RS20065 (H8S71_20060) vicX 3943575..3944369 (-) 795 WP_003242676.1 MBL fold metallo-hydrolase Regulator
  H8S71_RS20070 (H8S71_20065) walI 3944391..3945233 (-) 843 WP_029318542.1 WalRK two-component regulatory system regulator WalI -
  H8S71_RS20075 (H8S71_20070) walH 3945220..3946587 (-) 1368 WP_029318541.1 WalRK two-component regulatory system regulator WalH -
  H8S71_RS20080 (H8S71_20075) walK 3946577..3948412 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.5340

>NTDB_id=415119 H8S71_RS20060 WP_015250812.1 3942291..3943493(-) (htrA) [Bacillus subtilis subsp. subtilis strain ONU 559]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNTVTK
IVSNVSPAVVGVVNIQKSDIRGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=415119 H8S71_RS20060 WP_015250812.1 3942291..3943493(-) (htrA) [Bacillus subtilis subsp. subtilis strain ONU 559]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCAAG
CCTGATTGGTGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTAGATACGGGCG
CTTTAGATCAGCAGCAGAACAATAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATACGGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATACGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTATCAGCTGATCTTGTCGGCAGCGATCAGCTGATGGATCTG
GCCGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCATCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTTGACATCAAGCTGTCGTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(196-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.791

100

0.42
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.758

82.5

0.378
  htrA Streptococcus pneumoniae D39

45.758

82.5

0.378
  htrA Streptococcus pneumoniae Rx1

45.758

82.5

0.378
  htrA Streptococcus pneumoniae R6

45.758

82.5

0.378