Detailed information NTG0410742

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: GQ677_RS05555
• Genome accession: NZ_CP047120
• Coordinates: 1094164..1095000 (-)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 1085
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1089164..1100000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GQ677_RS05535 (GQ677_05535)	-	1089406..1090398 (-)	993	WP_010922317.1	D-lactate dehydrogenase	-
GQ677_RS05540 (GQ677_05540)	-	1090413..1090958 (-)	546	Protein_1029	PTS sugar transporter subunit IIC	-
GQ677_RS05545 (GQ677_05545)	-	1090971..1091853 (+)	883	Protein_1030	LysR family transcriptional regulator	-
GQ677_RS05550 (GQ677_05550)	topA	1091928..1094057 (-)	2130	WP_010922315.1	type I DNA topoisomerase	-
GQ677_RS05555 (GQ677_05555)	dprA	1094164..1095000 (-)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
GQ677_RS05560 (GQ677_05560)	-	1095065..1095856 (-)	792	WP_011285534.1	ribonuclease HII	-
GQ677_RS05565 (GQ677_05565)	ylqF	1095846..1096694 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
GQ677_RS05570 (GQ677_05570)	-	1096913..1097353 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
GQ677_RS05575 (GQ677_05575)	-	1097350..1098000 (+)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
GQ677_RS05580 (GQ677_05580)	-	1098117..1099028 (+)	912	WP_136273951.1	diacylglycerol kinase family protein	-
GQ677_RS05585 (GQ677_05585)	-	1099078..1099446 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=410742 GQ677_RS05555 WP_010922314.1 1094164..1095000(-) (dprA) [Streptococcus pyogenes strain 1085]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=410742 GQ677_RS05555 WP_010922314.1 1094164..1095000(-) (dprA) [Streptococcus pyogenes strain 1085]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367