Detailed information NTG0409423

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GPZ88_RS04720
• Genome accession: NZ_CP046919
• Coordinates: 919284..920162 (+)
• Length: 292 a.a.
• NCBI ID: WP_206282136.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_G2
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 914284..925162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPZ88_RS04690 (GPZ88_04650)	purD	914342..915604 (+)	1263	WP_074603841.1	phosphoribosylamine--glycine ligase	-
GPZ88_RS04695 (GPZ88_04655)	-	915594..916043 (+)	450	WP_074603839.1	DUF523 domain-containing protein	-
GPZ88_RS04700 (GPZ88_04660)	purE	916043..916531 (+)	489	WP_074603837.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
GPZ88_RS04705 (GPZ88_04665)	purK	916518..917609 (+)	1092	WP_166043586.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
GPZ88_RS10360 (GPZ88_04670)	-	917603..917707 (+)	105	Protein_899	phosphoribosylaminoimidazole carboxylase	-
GPZ88_RS04715 (GPZ88_04675)	purB	917797..919095 (+)	1299	WP_166043588.1	adenylosuccinate lyase	-
GPZ88_RS04720 (GPZ88_04680)	comR	919284..920162 (+)	879	WP_206282136.1	helix-turn-helix domain-containing protein	Regulator
GPZ88_RS04725 (GPZ88_04685)	ruvB	920364..921362 (+)	999	WP_074565269.1	Holliday junction branch migration DNA helicase RuvB	-
GPZ88_RS04730 (GPZ88_04690)	-	921535..922065 (+)	531	WP_074965577.1	DUF7010 family protein	-
GPZ88_RS04735 (GPZ88_04695)	-	922305..922736 (+)	432	WP_166043592.1	low molecular weight protein-tyrosine-phosphatase	-
GPZ88_RS04740 (GPZ88_04700)	-	922754..923134 (+)	381	WP_039696049.1	MORN repeat-containing protein	-
GPZ88_RS04745 (GPZ88_04705)	-	923131..924924 (+)	1794	WP_166043594.1	acyltransferase family protein	-

Sequence

Protein

• Length: 292 a.a.
• Molecular weight: 34378.10 Da
• Isoelectric Point: 4.5074

>NTDB_id=409423 GPZ88_RS04720 WP_206282136.1 919284..920162(+) (comR) [Streptococcus ruminicola strain CNU_G2]
MREEKGISREEFCGDETELSVRQLARIELNQSIPNLSKASFIANRLGVKLGTLTDGDSLELPKRYKELKYLLLRTPTYGD
QVRLDRKNDYFDEIAEVFYDVIPEEERLIIDCLQSKFDVHFSDDVNFGDGILNDYFDQVIHKETFNINDLILIDLYFACL
SSAKKFEGIYGLDFYDDLMKRLVNQKHISPETDLILNNVLLNNIDLAFQFKREYYIERVIAISEKIMTEIHDFQRRPILS
LVEWKYYLKFKHDFALAEQSFTNATLFARLVGDTYLENKLKEEWQLDIDAVE

Nucleotide

• Length: 879 bp

>NTDB_id=409423 GPZ88_RS04720 WP_206282136.1 919284..920162(+) (comR) [Streptococcus ruminicola strain CNU_G2]
ATGCGGGAGGAAAAAGGAATCTCACGCGAAGAATTCTGTGGAGATGAAACAGAATTATCGGTAAGACAATTAGCTAGAAT
TGAGTTGAACCAATCAATACCCAATCTCAGTAAAGCAAGCTTCATTGCCAATCGTCTGGGAGTGAAATTAGGTACCTTAA
CTGATGGTGACAGTTTAGAATTACCTAAGCGGTATAAAGAGTTGAAGTATTTACTTCTTCGAACACCTACATATGGAGAC
CAGGTACGACTTGATCGAAAAAATGACTATTTTGATGAGATTGCTGAAGTATTTTATGATGTTATTCCAGAAGAAGAAAG
GTTAATCATAGATTGTTTACAGTCAAAATTTGATGTTCATTTTAGTGACGACGTAAATTTTGGTGATGGTATTTTAAATG
ATTATTTTGATCAAGTTATTCATAAAGAGACTTTTAATATCAATGATTTAATTTTGATTGATCTTTACTTTGCTTGTCTT
TCTTCTGCTAAGAAGTTTGAAGGAATTTATGGTTTGGATTTTTACGACGATTTGATGAAAAGGTTGGTAAATCAGAAGCA
TATTTCACCTGAGACTGATTTAATTTTAAATAATGTATTGTTAAATAATATTGACTTAGCATTCCAATTTAAACGAGAAT
ATTATATTGAGCGTGTTATTGCAATCAGTGAAAAAATTATGACAGAGATTCATGATTTTCAACGTCGTCCGATTTTAAGT
TTGGTGGAGTGGAAGTATTATTTGAAATTTAAACATGATTTTGCTTTGGCAGAACAATCATTTACGAATGCAACATTATT
TGCACGATTGGTTGGTGATACTTATTTAGAAAATAAACTTAAAGAAGAATGGCAACTTGATATCGATGCTGTAGAGTAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (1-51)

• ComR tetratricopeptide (ComR_TPR) (62-284)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	95.548	100	0.955
comR	Streptococcus mutans UA159	54.167	98.63	0.534
comR	Streptococcus pyogenes MGAS8232	50	100	0.51
comR	Streptococcus pyogenes MGAS315	45.89	100	0.459
comR	Streptococcus suis D9	37.201	100	0.373
comR	Streptococcus suis P1/7	37.153	98.63	0.366
comR	Streptococcus suis 05ZYH33	37.153	98.63	0.366