Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GPZ88_RS04360 Genome accession   NZ_CP046919
Coordinates   865144..866400 (+) Length   418 a.a.
NCBI ID   WP_158914651.1    Uniprot ID   A0A6G8HZL7
Organism   Streptococcus ruminicola strain CNU_G2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 860144..871400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS04335 (GPZ88_04295) - 861055..863631 (+) 2577 WP_166043575.1 YfhO family protein -
  GPZ88_RS04355 (GPZ88_04315) rlmH 864449..864928 (-) 480 WP_039696083.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GPZ88_RS04360 (GPZ88_04320) htrA 865144..866400 (+) 1257 WP_158914651.1 S1C family serine protease Regulator
  GPZ88_RS04365 (GPZ88_04325) spo0J 866467..867249 (+) 783 WP_158914653.1 ParB/RepB/Spo0J family partition protein Regulator
  GPZ88_RS04370 (GPZ88_04330) dnaA 867453..868808 (+) 1356 WP_039696081.1 chromosomal replication initiator protein DnaA -
  GPZ88_RS04375 (GPZ88_04335) dnaN 868967..870103 (+) 1137 WP_158914655.1 DNA polymerase III subunit beta -
  GPZ88_RS04380 (GPZ88_04340) - 870234..871118 (+) 885 WP_166043577.1 diacylglycerol/lipid kinase family protein -
  GPZ88_RS04385 (GPZ88_04345) - 871129..871320 (+) 192 WP_039696077.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 43360.56 Da        Isoelectric Point: 4.7392

>NTDB_id=409421 GPZ88_RS04360 WP_158914651.1 865144..866400(+) (htrA) [Streptococcus ruminicola strain CNU_G2]
MKKIKFRKVNYKKILKPLSVILVGFIGGVAGTLLILNMAGISINNVSGSSAKTTTSKVSYSNTNDTTKAVEKVGEAVVSV
INYQSNSSSNDLYMQMFGGNLDNNTNNNGSDSDLSIASEGSGVIYKKDGNSAYVVTNNHVVDGASQIEIMLSDGTKVVGE
LVGADTYSDIAVVKIASDKVTTVAEFADSDKITVGETAIAIGSPLGTDYANSVTQGIVSSLSRTVTMTNDDGETISTNAI
QTDAAINPGNSGGALINIEGQVIGINSSKISSTSDSGSGNSVEGMGFAIPANDVVKIINQLEANGKVIRPALGITMANLS
DLSTTTISRLNIPTSVTAGIVVASVQSGMPAEGALKKYDVITAIDDKDVSSITDLQSVLYGHSTGDSIKVTFYRGTDKKT
ETIKLTKTTQDLSSSSNQ

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=409421 GPZ88_RS04360 WP_158914651.1 865144..866400(+) (htrA) [Streptococcus ruminicola strain CNU_G2]
GTGAAAAAAATAAAATTTCGAAAAGTCAATTACAAAAAAATCCTTAAACCACTCTCAGTTATTTTAGTGGGATTCATTGG
AGGAGTTGCTGGGACCTTACTCATTTTGAATATGGCTGGCATCTCAATCAATAATGTTAGTGGTTCAAGTGCAAAAACTA
CAACAAGTAAAGTAAGTTACTCAAATACTAATGATACGACGAAAGCTGTCGAAAAAGTGGGAGAAGCAGTCGTATCAGTC
ATCAATTATCAATCAAATAGCTCTTCAAATGATTTGTATATGCAAATGTTTGGAGGCAATTTAGACAATAACACTAATAA
TAATGGATCAGATAGTGATTTAAGCATCGCTAGTGAAGGTTCAGGGGTTATTTACAAAAAAGACGGCAATTCTGCTTACG
TCGTTACTAATAACCACGTTGTCGATGGTGCTAGCCAAATCGAAATCATGCTTTCTGACGGTACAAAAGTAGTCGGTGAA
TTAGTCGGTGCCGATACATACTCAGATATCGCCGTTGTCAAAATTGCTTCTGATAAAGTCACAACGGTAGCTGAATTTGC
TGATTCAGATAAAATTACTGTTGGTGAAACAGCCATTGCTATTGGTAGCCCTCTAGGTACTGATTACGCTAACTCAGTAA
CCCAAGGAATTGTCTCAAGTCTAAGCCGTACAGTTACAATGACTAACGACGATGGCGAAACAATTTCAACTAATGCTATC
CAAACTGATGCCGCTATTAACCCAGGTAACTCTGGTGGTGCTTTGATTAACATTGAAGGACAAGTGATCGGTATTAATTC
AAGTAAAATTTCTTCTACCTCAGATTCTGGATCAGGTAATTCTGTAGAAGGTATGGGATTTGCTATTCCAGCTAATGATG
TGGTTAAAATTATTAATCAATTAGAAGCAAACGGAAAAGTTATCCGTCCAGCACTTGGCATCACAATGGCTAACCTAAGC
GATTTATCAACAACAACAATCAGTCGCCTAAATATTCCAACTAGCGTCACAGCTGGTATCGTCGTTGCTTCAGTTCAATC
AGGTATGCCTGCTGAAGGAGCACTTAAAAAATACGATGTCATCACAGCTATCGATGATAAAGATGTTTCTTCTATCACAG
ATCTTCAAAGTGTCCTTTACGGTCATTCAACTGGAGATTCTATTAAAGTAACCTTCTATCGTGGTACTGATAAGAAAACA
GAAACTATTAAACTAACGAAAACAACACAAGACCTCTCTTCATCATCAAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(120-265)

Peptidase family M50 (Peptidase_M50)

(78-411)

PDZ domain (PDZ_2)

(310-405)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HZL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

64.179

96.172

0.617
  htrA Streptococcus gordonii str. Challis substr. CH1

60.494

96.89

0.586
  htrA Streptococcus mitis NCTC 12261

58.981

98.565

0.581
  htrA Streptococcus pneumoniae TIGR4

58.738

98.565

0.579
  htrA Streptococcus pneumoniae D39

58.738

98.565

0.579
  htrA Streptococcus pneumoniae Rx1

58.738

98.565

0.579
  htrA Streptococcus pneumoniae R6

58.738

98.565

0.579

Multiple sequence alignment