Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   GP482_RS08410 Genome accession   NZ_CP046875
Coordinates   1708124..1709032 (+) Length   302 a.a.
NCBI ID   WP_074603833.1    Uniprot ID   A0AAE8HMM3
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1706587..1707938 1708124..1709032 flank 186


Gene organization within MGE regions


Location: 1706587..1709032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS08410 (GP482_08410) comR 1708124..1709032 (+) 909 WP_074603833.1 XRE family transcriptional regulator Regulator

Sequence

Protein


Download         Length: 302 a.a.        Molecular weight: 35644.76 Da        Isoelectric Point: 4.7177

>NTDB_id=409142 GP482_RS08410 WP_074603833.1 1708124..1709032(+) (comR) [Streptococcus ruminicola strain CNU_77-61]
MEKFGEKIRLMREEKGISREEFCGDETELSVRQLARIELNQSIPNLSKASFIANRLGVKLGTLTDGDSLELPKRYKELKY
LLLRTPTYGDQVRLDRKNDYFDEIAEVFYDVIPEEERLIIDCLQSKFDVHFSEDVNFGEGILNDYFGQVNRKKVFTINDL
ILIDLYFACLSSAKKFEGIYSLDFYDDLMKRLVNQKHISPETDLILNNVLLNNIDLAFQFKREYYIERVIAISEKIMTEI
HDFQRRPILSLVEWKYYLKFKHDFTLAEQSFTNATLFARLVGDTYLENKLKEEWQLDIDAVE

Nucleotide


Download         Length: 909 bp        

>NTDB_id=409142 GP482_RS08410 WP_074603833.1 1708124..1709032(+) (comR) [Streptococcus ruminicola strain CNU_77-61]
GTGGAAAAATTTGGGGAGAAGATCCGCTTGATGCGGGAGGAAAAGGGAATCTCACGCGAAGAATTCTGTGGGGATGAAAC
AGAATTATCGGTAAGACAATTAGCTAGAATTGAGTTGAACCAATCAATACCCAATCTCAGTAAAGCAAGCTTCATTGCCA
ATCGTCTGGGAGTGAAATTAGGTACCTTAACTGATGGTGACAGTTTAGAATTACCTAAGCGGTATAAAGAGTTGAAGTAT
TTACTTCTTCGAACACCTACATATGGAGACCAGGTACGACTTGATCGAAAAAATGACTATTTTGATGAGATTGCTGAAGT
ATTTTATGATGTTATTCCAGAAGAAGAACGGTTAATCATTGATTGTTTACAATCAAAATTCGATGTTCATTTTAGTGAAG
ATGTCAATTTTGGAGAGGGTATTTTAAATGATTATTTTGGTCAAGTTAATCGAAAGAAAGTTTTTACCATTAATGATTTA
ATTTTGATTGATCTTTACTTTGCTTGTCTTTCTTCTGCTAAGAAGTTTGAAGGAATTTATAGTTTGGATTTTTACGACGA
TTTGATGAAAAGGTTGGTAAATCAAAAGCATATTTCACCTGAGACTGATTTAATTTTAAATAATGTATTGTTAAATAATA
TTGACTTAGCATTCCAATTTAAACGAGAATATTATATTGAGCGTGTTATTGCAATCAGTGAAAAAATTATGACAGAGATT
CATGATTTTCAACGTCGTCCGATTTTAAGTTTGGTGGAGTGGAAGTATTATCTGAAATTTAAACATGACTTTACTTTAGC
AGAACAATCATTTACGAATGCAACATTATTTGCACGATTGGTTGGTGATACTTATTTAGAAAATAAACTTAAAGAAGAAT
GGCAACTTGATATCGATGCTGTGGAGTAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(8-61)

ComR tetratricopeptide (ComR_TPR)

(72-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

98.288

96.689

0.95
  comR Streptococcus mutans UA159

53.02

98.675

0.523
  comR Streptococcus pyogenes MGAS8232

50.993

100

0.51
  comR Streptococcus pyogenes MGAS315

45.695

100

0.457
  comR Streptococcus suis P1/7

37.374

98.344

0.368
  comR Streptococcus suis 05ZYH33

37.374

98.344

0.368
  comR Streptococcus suis D9

36.424

100

0.364

Multiple sequence alignment