Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GP482_RS03580 Genome accession   NZ_CP046875
Coordinates   722089..722763 (-) Length   224 a.a.
NCBI ID   WP_074563738.1    Uniprot ID   A0AAE8HJU5
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 717089..727763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS03555 (GP482_03555) deoC 717546..718211 (-) 666 WP_074625712.1 deoxyribose-phosphate aldolase -
  GP482_RS03560 (GP482_03560) - 718713..719306 (-) 594 WP_157629041.1 class I SAM-dependent methyltransferase -
  GP482_RS03565 (GP482_03565) coaA 719438..720358 (+) 921 WP_158913875.1 type I pantothenate kinase -
  GP482_RS03570 (GP482_03570) rpsT 720434..720685 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  GP482_RS03575 (GP482_03575) ciaH 720771..722099 (-) 1329 WP_039696862.1 HAMP domain-containing sensor histidine kinase Regulator
  GP482_RS03580 (GP482_03580) ciaR 722089..722763 (-) 675 WP_074563738.1 response regulator transcription factor Regulator
  GP482_RS03585 (GP482_03585) - 722930..725473 (-) 2544 WP_157629043.1 M1 family metallopeptidase -
  GP482_RS03590 (GP482_03590) phoU 725703..726356 (-) 654 WP_039696860.1 phosphate signaling complex protein PhoU -
  GP482_RS03595 (GP482_03595) pstB 726387..727145 (-) 759 WP_039696859.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25487.09 Da        Isoelectric Point: 4.3047

>NTDB_id=409109 GP482_RS03580 WP_074563738.1 722089..722763(-) (ciaR) [Streptococcus ruminicola strain CNU_77-61]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREQGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNDNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTNFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=409109 GP482_RS03580 WP_074563738.1 722089..722763(-) (ciaR) [Streptococcus ruminicola strain CNU_77-61]
ATGATTAAGATTTTATTAGTAGAAGATGATTTGAGTTTATCGAATTCAATCTTTGATTTTTTAGATGATTTTGCAGATGT
TATGCAAGTCTTTGATGGTGAAGAAGGGCTTTATGAGGCAGAAAGTGGTGTTTATGACCTCATTTTGCTTGATCTGATGT
TGCCAGAAAAAGATGGTTTCCAAGTTCTAAAAGAATTACGTGAACAAGGTATTACGACACCTGTCTTAATTATGACAGCC
AAAGAAAGCCTTGATGATAAAGGACACGGTTTTGAACTTGGTGCTGATGATTATTTGACAAAACCATTTTATCTTGAAGA
GTTGAAGATGCGTATTCAAGCGCTTTTGAAACGCTCTGGAAAATTCAATGATAATACTCTTTCTTACCACGAATTAACAG
CTGATACATCAACTAACACAACAACTGTTAACGGTGAAAAAGTGGAGTTACTAGGTAAAGAATTTGATTTATTGGTTTAT
TTCTTGCAAAACCAAAATGTTATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGATTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGCAAAAAATTAAAAGGGACAAATTTTGCTAAAAATCTACAAACACTTC
GTAGTGTAGGGTATATTCTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.946

100

0.879
  ciaR Streptococcus pneumoniae D39

87.946

100

0.879
  ciaR Streptococcus pneumoniae R6

87.946

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.326

100

0.388
  vicR Streptococcus mutans UA159

34.764

100

0.362

Multiple sequence alignment