Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GP482_RS03575 Genome accession   NZ_CP046875
Coordinates   720771..722099 (-) Length   442 a.a.
NCBI ID   WP_039696862.1    Uniprot ID   A0A091BVP1
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 715771..727099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS03550 (GP482_03550) - 716288..717352 (-) 1065 WP_039696865.1 BMP family protein -
  GP482_RS03555 (GP482_03555) deoC 717546..718211 (-) 666 WP_074625712.1 deoxyribose-phosphate aldolase -
  GP482_RS03560 (GP482_03560) - 718713..719306 (-) 594 WP_157629041.1 class I SAM-dependent methyltransferase -
  GP482_RS03565 (GP482_03565) coaA 719438..720358 (+) 921 WP_158913875.1 type I pantothenate kinase -
  GP482_RS03570 (GP482_03570) rpsT 720434..720685 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  GP482_RS03575 (GP482_03575) ciaH 720771..722099 (-) 1329 WP_039696862.1 HAMP domain-containing sensor histidine kinase Regulator
  GP482_RS03580 (GP482_03580) ciaR 722089..722763 (-) 675 WP_074563738.1 response regulator transcription factor Regulator
  GP482_RS03585 (GP482_03585) - 722930..725473 (-) 2544 WP_157629043.1 M1 family metallopeptidase -
  GP482_RS03590 (GP482_03590) phoU 725703..726356 (-) 654 WP_039696860.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 50098.00 Da        Isoelectric Point: 6.6262

>NTDB_id=409108 GP482_RS03575 WP_039696862.1 720771..722099(-) (ciaH) [Streptococcus ruminicola strain CNU_77-61]
MLNNIHKKLSTGTFSNFFHFFIVFTGIFIIMTTIILQIMRYGLYSSVDTTLKNAADNASDYVTRTMERSDSLQSNNSFSN
SGKGKPSSNVASLSNVSVLLYDTNGKIVNAIDAFVQFGTLASSVDEDTIGEIKDEKMTTIFGQTEKYHVLTVRVYSSDYP
TIEYATFLISVSQLDEANERYVTITVSVMIIFWMISILASIYLANWMRKPILESYEKQKRFVENASHELRTPLAVLQNRL
ESLFRRPNATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIQPSIFNEIFENYNMIAEENGKTFVAHNS
ADRPIKTDRTLLKQLMTILFDNAIKYTDDDGFIEFTVKTTERQTILTVADNGPGISDADKAKIFDRFYRVDKARTRQKGG
FGLGLSLAKQIVDALKGDIQVKDNHPKGTIFEVRFNRHNFGK

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=409108 GP482_RS03575 WP_039696862.1 720771..722099(-) (ciaH) [Streptococcus ruminicola strain CNU_77-61]
ATGCTGAATAACATACACAAAAAATTATCAACAGGAACGTTTTCTAATTTTTTCCATTTCTTCATTGTATTTACAGGAAT
TTTCATCATTATGACCACGATTATCTTGCAGATTATGCGTTATGGTCTATATTCTTCTGTAGATACCACTTTAAAAAATG
CAGCTGACAACGCAAGTGATTACGTCACACGAACAATGGAGCGTAGTGATTCCTTACAATCTAATAATAGTTTTAGTAAT
TCTGGAAAAGGAAAACCCAGCTCAAATGTGGCAAGTTTAAGTAATGTCAGTGTGCTATTGTACGATACAAATGGAAAAAT
CGTAAATGCAATTGATGCGTTTGTCCAGTTTGGGACATTAGCATCTAGTGTTGATGAAGACACTATTGGTGAGATTAAAG
ACGAGAAAATGACAACTATCTTTGGTCAAACCGAAAAATACCATGTTTTAACGGTTAGAGTGTATAGTAGTGACTATCCA
ACGATTGAATACGCGACTTTCTTAATCAGTGTTAGTCAGCTTGATGAGGCAAACGAACGTTATGTAACCATAACTGTTTC
AGTCATGATTATTTTCTGGATGATTTCAATTTTAGCAAGTATTTACTTGGCAAATTGGATGCGTAAACCAATTTTAGAAA
GTTATGAAAAACAAAAGCGTTTTGTTGAAAATGCTAGTCACGAATTAAGAACGCCGTTAGCGGTGCTTCAAAACCGACTT
GAAAGTCTTTTTAGACGGCCGAATGCAACAATTCTTGATAACAGTGAAAGTATTGCAGCGAGTCTTGACGAAGTTCGTAA
TATGCGTATTTTAACAACCAATCTTTTGAACCTTGCTAGGCGAGATGATGGATTGAAAGTTGAATTAGAAGAAATCCAAC
CTTCAATCTTTAATGAAATTTTTGAGAATTACAACATGATTGCCGAAGAAAATGGTAAAACTTTTGTTGCTCATAATTCT
GCGGATCGTCCGATAAAAACTGATCGCACCTTGCTTAAACAATTGATGACAATCTTGTTTGATAATGCGATTAAGTACAC
TGATGACGACGGTTTTATTGAATTTACAGTTAAAACAACAGAACGCCAGACTATTCTAACCGTCGCTGATAATGGGCCGG
GTATTAGTGACGCTGATAAAGCGAAAATTTTTGATCGCTTTTATCGCGTTGATAAGGCAAGGACACGTCAAAAAGGTGGC
TTTGGACTTGGTCTATCCTTAGCTAAACAAATTGTTGATGCCTTAAAAGGTGATATTCAAGTTAAGGATAATCATCCAAA
AGGAACTATCTTTGAAGTTCGTTTTAACCGACATAATTTTGGTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(218-284)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(328-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A091BVP1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.54

98.416

0.586
  ciaH Streptococcus pneumoniae Rx1

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae D39

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae R6

52.174

98.869

0.516
  ciaH Streptococcus pneumoniae TIGR4

52.174

98.869

0.516

Multiple sequence alignment