Detailed information NTG0406288

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GPA00_RS03295
• Genome accession: NZ_CP046629
• Coordinates: 654934..655839 (+)
• Length: 301 a.a.
• NCBI ID: WP_198362634.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU G6
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 649934..660839

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS03270 (GPA00_03270)	-	651127..651576 (+)	450	WP_027968249.1	DUF523 domain-containing protein	-
GPA00_RS03275 (GPA00_03275)	purE	651576..652064 (+)	489	WP_021141395.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
GPA00_RS03280 (GPA00_03280)	purK	652051..653142 (+)	1092	WP_021141396.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
GPA00_RS03285 (GPA00_03285)	-	653164..653388 (+)	225	WP_157327509.1	phosphoribosylaminoimidazole carboxylase	-
GPA00_RS03290 (GPA00_03290)	purB	653479..654777 (+)	1299	WP_024344772.1	adenylosuccinate lyase	-
GPA00_RS03295 (GPA00_03295)	comR	654934..655839 (+)	906	WP_198362634.1	helix-turn-helix domain-containing protein	Regulator
GPA00_RS03300 (GPA00_03300)	ruvB	656010..657008 (+)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
GPA00_RS03305 (GPA00_03305)	-	657218..657649 (+)	432	WP_074484049.1	low molecular weight protein-tyrosine-phosphatase	-
GPA00_RS03310 (GPA00_03310)	-	657666..658046 (+)	381	WP_074451189.1	MORN repeat-containing protein	-
GPA00_RS03315 (GPA00_03315)	-	658043..659836 (+)	1794	WP_157327513.1	acyltransferase family protein	-

Sequence

Protein

• Length: 301 a.a.
• Molecular weight: 35250.53 Da
• Isoelectric Point: 4.7525

>NTDB_id=406288 GPA00_RS03295 WP_198362634.1 654934..655839(+) (comR) [Streptococcus equinus strain CNU G6]
MKKLGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKELKY
LILRTPTYKDEKRVNLRDSYFDEIYSDFYDDLPEEEQLIVECMRSKADVFLTDNSNLATKLLEDYFYQTKSKSHYSINDL
IIIDLYMVCANASNYEYFMFDKDEFIGIAKNLLEQENHFSLAEIFVLNNILFGSLSLLVDLKMWDEVELTLDVLKGIMAK
IQDFHKKPVLNMIEWKYILERFGQTEKAQKLYEEAVLYANLIGDVYLANKITEEWIKDTTA

Nucleotide

• Length: 906 bp

>NTDB_id=406288 GPA00_RS03295 WP_198362634.1 654934..655839(+) (comR) [Streptococcus equinus strain CNU G6]
GTGAAAAAATTGGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGTGAAGAATTCTGTGGGGACGAGAC
CGAATTATCCGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGCCCAATTCATTGCTA
ATCGCCTTGGCGTAAAACTCGGAACCCTGACAGATGGCGATAGCTTAGAATTACCAAAGCGGTATAAAGAGCTGAAGTAT
TTAATTTTGCGTACGCCAACGTATAAAGATGAAAAGCGTGTGAATTTAAGAGATTCTTATTTTGATGAGATTTACTCTGA
CTTTTACGATGACCTTCCTGAGGAGGAGCAATTAATCGTGGAGTGCATGCGCTCAAAAGCAGATGTCTTTTTAACTGATA
ATAGTAATTTAGCCACAAAGTTGTTAGAAGACTATTTTTATCAAACAAAATCAAAATCGCATTATTCGATTAATGACTTA
ATCATAATTGATTTATATATGGTTTGTGCGAATGCTTCAAATTATGAATATTTTATGTTTGATAAAGATGAATTTATTGG
TATAGCTAAGAATCTATTAGAACAAGAAAATCACTTTTCGCTAGCAGAAATTTTTGTCTTAAATAATATTTTATTTGGTA
GTTTGAGCTTGTTGGTTGATTTAAAAATGTGGGACGAAGTGGAATTGACTTTAGATGTTTTAAAAGGAATTATGGCTAAA
ATTCAAGATTTTCATAAGAAGCCAGTTTTGAACATGATTGAGTGGAAGTATATTTTGGAACGTTTTGGTCAAACAGAAAA
GGCTCAAAAATTATATGAAGAGGCAGTGTTATATGCAAATTTGATAGGTGATGTTTATTTAGCCAATAAAATAACAGAAG
AATGGATAAAAGATACAACAGCATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

• Helix-turn-helix (HTH_3) (8-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.234	96.678	0.505
comR	Streptococcus pyogenes MGAS8232	46.512	100	0.465
comR	Streptococcus mutans UA159	46.488	99.336	0.462
comR	Streptococcus pyogenes MGAS315	45.973	99.003	0.455
comR	Streptococcus suis P1/7	39.456	97.674	0.385
comR	Streptococcus suis 05ZYH33	39.456	97.674	0.385
comR	Streptococcus suis D9	37.134	100	0.379