Detailed information NTG0406248

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: GO596_RS05485
• Genome accession: NZ_CP046628
• Coordinates: 1093435..1094145 (+)
• Length: 236 a.a.
• NCBI ID: WP_021142846.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU 77-23
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1088435..1099145

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO596_RS05455 (GO596_05455)	-	1089018..1089314 (+)	297	WP_157339346.1	hypothetical protein	-
GO596_RS05460 (GO596_05460)	-	1089532..1090140 (+)	609	WP_021142851.1	TVP38/TMEM64 family protein	-
GO596_RS05465 (GO596_05465)	-	1090172..1090819 (-)	648	WP_004232801.1	amino acid ABC transporter permease	-
GO596_RS05470 (GO596_05470)	-	1090829..1091533 (-)	705	WP_004232799.1	amino acid ABC transporter permease	-
GO596_RS05475 (GO596_05475)	-	1091549..1092358 (-)	810	WP_157339347.1	transporter substrate-binding domain-containing protein	-
GO596_RS05480 (GO596_05480)	-	1092363..1093127 (-)	765	WP_024343734.1	amino acid ABC transporter ATP-binding protein	-
GO596_RS05485 (GO596_05485)	vicR	1093435..1094145 (+)	711	WP_021142846.1	response regulator YycF	Regulator
GO596_RS05490 (GO596_05490)	vicK	1094138..1095490 (+)	1353	WP_024343735.1	cell wall metabolism sensor histidine kinase VicK	Regulator
GO596_RS05495 (GO596_05495)	vicX	1095491..1096300 (+)	810	WP_157339348.1	MBL fold metallo-hydrolase	Regulator
GO596_RS05505 (GO596_05505)	-	1096676..1096990 (+)	315	WP_000420682.1	YdcP family protein	-
GO596_RS05510 (GO596_05510)	-	1097006..1097392 (+)	387	WP_157339349.1	YdcP family protein	-
GO596_RS05515 (GO596_05515)	-	1097421..1098806 (+)	1386	WP_000813488.1	FtsK/SpoIIIE domain-containing protein	-
GO596_RS05520 (GO596_05520)	-	1098809..1098961 (+)	153	WP_000879507.1	hypothetical protein	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27179.94 Da
• Isoelectric Point: 4.6553

>NTDB_id=406248 GO596_RS05485 WP_021142846.1 1093435..1094145(+) (vicR) [Streptococcus equinus strain CNU 77-23]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIEKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide

• Length: 711 bp

>NTDB_id=406248 GO596_RS05485 WP_021142846.1 1093435..1094145(+) (vicR) [Streptococcus equinus strain CNU 77-23]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAATTTAACTAAAGAAGGTTACGA
AACAGTTACGGCTTTTGATGGTCGTGAAGCTATTGAAAAATTTGAAGAAGAAAATCCTGATTTGATTATTTTGGATTTGA
TGTTGCCAGAATTGGATGGACTTGAAGTCGCAAAAGAAGTTCGTAAAACAAGTCATATTCCTATTATTATGCTATCAGCA
AAAGATAGTGAATTTGATAAAGTTATCGGTCTTGAAATCGGTGCTGACGACTACGTGACAAAACCATTTTCAAACCGCGA
ATTGTTGGCTCGTGTCAAAGCACACCTTCGCCGCACTGAAAATATCGAATCTGCAGTTGCTGAAGAAAATGCGTCTTCTT
CAAACTCAGAAATCACAATTGGTGACTTGAAAATCTTGCCTGATGCATTTGTGGCACAAAAACGTGGTGAAGACATTGAA
TTAACACACCGTGAGTTTGAATTGTTGCACCATTTGGCAACTCACATGGGACAAGTAATGACACGTGAATACCTTTTGGA
AACTGTTTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGACGTGACAATCCGTCGTTTACGTGAAAAAATCGAAG
ACACACCAAGTCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGATATTACATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (156-231)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	90.678	100	0.907
micA	Streptococcus pneumoniae Cp1015	78.632	99.153	0.78
covR	Streptococcus salivarius strain HSISS4	47.414	98.305	0.466
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.121	98.305	0.453
scnR	Streptococcus mutans UA159	36.864	100	0.369