Detailed information NTG0406238

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: GO596_RS03970
• Genome accession: NZ_CP046628
• Coordinates: 790219..790950 (+)
• Length: 243 a.a.
• NCBI ID: WP_157339238.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU 77-23
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 785219..795950

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO596_RS03935 (GO596_03935)	-	785301..785825 (+)	525	WP_157339234.1	DUF1697 domain-containing protein	-
GO596_RS03940 (GO596_03940)	rsmA	785907..786779 (+)	873	WP_157339235.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
GO596_RS03945 (GO596_03945)	-	787346..787525 (+)	180	WP_039691373.1	hypothetical protein	-
GO596_RS03950 (GO596_03950)	-	787572..787877 (-)	306	Protein_704	cysteine peptidase family C39 domain-containing protein	-
GO596_RS09535	-	788112..788222 (+)	111	WP_232516872.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
GO596_RS03955 (GO596_03955)	-	788189..788350 (+)	162	WP_232516873.1	hypothetical protein	-
GO596_RS03960 (GO596_03960)	-	788416..788727 (+)	312	WP_061408660.1	hypothetical protein	-
GO596_RS03965 (GO596_03965)	-	788917..789528 (+)	612	WP_157339237.1	thioredoxin family protein	-
GO596_RS03970 (GO596_03970)	comE/comE1	790219..790950 (+)	732	WP_157339238.1	response regulator transcription factor	Regulator
GO596_RS03975 (GO596_03975)	-	790955..792265 (+)	1311	WP_157339239.1	sensor histidine kinase	-
GO596_RS09440	comC/comC1	792286..792432 (-)	147	WP_169741101.1	hypothetical protein	Regulator
GO596_RS03980 (GO596_03980)	-	792620..792916 (+)	297	WP_157339240.1	DUF3884 family protein	-
GO596_RS03985 (GO596_03985)	-	792936..793241 (+)	306	WP_024344359.1	bacteriocin immunity protein	-
GO596_RS03990 (GO596_03990)	-	793273..793566 (+)	294	WP_157339241.1	bacteriocin immunity protein	-
GO596_RS03995 (GO596_03995)	comD/comD3	793914..795104 (+)	1191	WP_232516874.1	sensor histidine kinase	Regulator

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28023.93 Da
• Isoelectric Point: 6.1634

>NTDB_id=406238 GO596_RS03970 WP_157339238.1 790219..790950(+) (comE/comE1) [Streptococcus equinus strain CNU 77-23]
MLDIFILEDNITQQFRIERQIEAIMEKNNWAYQHLEAFAASEDIIAKASEKKSHQIFFLDLEIKGDEKQGIDVARAIREK
DSTAIIVFVTTHSEFMLLTYQSLVGAIDFIDKNLNDVAFEQRLELCLKEALKHQKGNLGENSYLFETAKARIRVAYDDIL
YFETSPTVHRVILHTKTGQTEFYGTIAEVAKSDERLFKCHRSFVINVNNVAEFNKSTRTAYFANGSYCQVSRDKVKSLMA
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=406238 GO596_RS03970 WP_157339238.1 790219..790950(+) (comE/comE1) [Streptococcus equinus strain CNU 77-23]
ATGTTAGATATTTTTATCCTTGAGGATAATATCACACAACAATTTCGTATTGAGCGACAGATAGAGGCAATTATGGAAAA
GAATAATTGGGCTTATCAGCACTTGGAAGCTTTTGCGGCATCTGAGGATATTATTGCAAAAGCATCTGAAAAGAAGAGCC
ATCAGATTTTCTTTCTTGATTTAGAAATTAAAGGGGATGAAAAGCAAGGAATTGACGTGGCAAGAGCCATCCGTGAGAAG
GATTCAACAGCTATTATTGTTTTTGTAACGACTCATTCTGAGTTTATGCTTTTAACTTATCAGTCGTTGGTTGGTGCGAT
TGATTTCATTGATAAAAATTTAAATGATGTAGCTTTTGAACAACGTCTAGAGTTATGCTTGAAGGAAGCTCTTAAGCATC
AAAAAGGAAATTTAGGTGAGAATTCTTACCTTTTTGAAACTGCCAAAGCGAGAATTCGTGTAGCTTACGATGATATTTTA
TATTTTGAAACATCGCCAACCGTCCACCGAGTGATTTTACACACAAAAACAGGTCAAACTGAATTTTACGGAACGATTGC
GGAGGTTGCCAAATCAGATGAACGTCTGTTCAAATGTCACCGCTCTTTTGTGATTAATGTAAATAATGTTGCTGAATTTA
ATAAAAGTACCCGAACAGCTTATTTTGCAAATGGCTCTTACTGCCAAGTCTCACGAGACAAAGTCAAAAGCCTAATGGCA
GAAATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (4-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	87.243	100	0.872
comE/comE2	Streptococcus equinus JB1	47.521	99.588	0.473
comE/blpR	Streptococcus mutans UA159	46.058	99.177	0.457
comE/comE2	Streptococcus gordonii strain NCTC7865	35.341	100	0.362
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	35.341	100	0.362