Detailed information NTG0406230

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GO596_RS02835
• Genome accession: NZ_CP046628
• Coordinates: 564961..565869 (-)
• Length: 302 a.a.
• NCBI ID: WP_049805804.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU 77-23
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 559961..570869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO596_RS02815 (GO596_02815)	-	560962..562755 (-)	1794	WP_157339175.1	acyltransferase family protein	-
GO596_RS02820 (GO596_02820)	-	562752..563132 (-)	381	WP_021141401.1	MORN repeat-containing protein	-
GO596_RS02825 (GO596_02825)	-	563149..563580 (-)	432	WP_021141400.1	low molecular weight protein-tyrosine-phosphatase	-
GO596_RS02830 (GO596_02830)	ruvB	563790..564788 (-)	999	WP_021141399.1	Holliday junction branch migration DNA helicase RuvB	-
GO596_RS02835 (GO596_02835)	comR	564961..565869 (-)	909	WP_049805804.1	helix-turn-helix domain-containing protein	Regulator
GO596_RS02840 (GO596_02840)	purB	566019..567317 (-)	1299	WP_024344772.1	adenylosuccinate lyase	-
GO596_RS02845 (GO596_02845)	purK	567458..568549 (-)	1092	WP_157339176.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
GO596_RS02850 (GO596_02850)	purE	568536..569024 (-)	489	WP_021141395.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
GO596_RS02855 (GO596_02855)	-	569024..569473 (-)	450	WP_157339692.1	DUF523 domain-containing protein	-
GO596_RS02860 (GO596_02860)	purD	569463..570725 (-)	1263	WP_157339177.1	phosphoribosylamine--glycine ligase	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35531.45 Da
• Isoelectric Point: 4.6836

>NTDB_id=406230 GO596_RS02835 WP_049805804.1 564961..565869(-) (comR) [Streptococcus equinus strain CNU 77-23]
MEVKKFGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKEL
KYLLLRTPTYGDQERVDRKNDYFDEISENYYDIIPEEEKLIIDCLQSKFDVHFSDDVNFGDGILNDYFDQVIRKETFNIN
DLILIDLYCVCMASAKAYTGIYSLDIYDNLMDCLLNQSHVTPETSLILNNVLLNNIALAFQFEREDYVYKVIKISDRIMT
EIHDFQRRPILSLVEWKYYLKFKHDYDSAKQSFTNATLFARLIGDVYLENKLKEEWEFDTTT

Nucleotide

• Length: 909 bp

>NTDB_id=406230 GO596_RS02835 WP_049805804.1 564961..565869(-) (comR) [Streptococcus equinus strain CNU 77-23]
ATGGAAGTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAGAAGGGAATCTCACGCGAAGAATTCTGTGGGGA
CGAGACCGAATTATCCGTACGACAACTAGCACGAATTGAGCTAAACCAATCGATACCTAACCTAAGTAAAGCCCAATTCA
TTGCTAATCGCCTTGGCGTAAAACTTGGAACCCTGACAGACGGCGATAGCTTAGAATTACCAAAGCGGTATAAAGAGCTG
AAGTATTTGTTGCTTAGGACACCGACATATGGCGATCAAGAGAGAGTTGATCGGAAAAATGATTATTTTGATGAGATATC
AGAGAATTATTACGATATTATTCCTGAAGAAGAGAAACTCATCATAGATTGTTTACAGTCAAAATTTGATGTTCATTTTA
GTGACGACGTAAATTTTGGTGATGGTATTTTAAATGATTATTTTGATCAAGTTATTCGTAAAGAGACTTTTAATATCAAT
GATTTAATTTTGATTGATCTTTACTGTGTATGCATGGCATCCGCTAAAGCGTATACCGGAATTTACAGTTTGGATATTTA
TGATAATTTGATGGATTGTTTATTAAATCAAAGTCATGTTACGCCGGAGACTAGTTTGATTTTGAATAATGTGTTGTTAA
ATAATATTGCTCTGGCTTTTCAATTTGAACGAGAAGACTACGTTTATAAAGTGATTAAGATAAGCGATAGGATTATGACT
GAGATTCATGATTTTCAACGTCGCCCAATTTTAAGCTTAGTTGAATGGAAATATTATTTGAAGTTTAAACATGATTATGA
CAGTGCAAAACAATCTTTTACAAACGCAACTTTATTTGCAAGATTAATCGGTGATGTTTACTTAGAGAACAAACTTAAAG
AAGAATGGGAATTCGATACAACAACATGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (74-296)

• Helix-turn-helix (HTH_3) (10-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	82.23	95.033	0.781
comR	Streptococcus mutans UA159	52.508	99.007	0.52
comR	Streptococcus pyogenes MGAS8232	50.331	100	0.503
comR	Streptococcus pyogenes MGAS315	44.631	98.675	0.44
comR	Streptococcus suis D9	38.614	100	0.387
comR	Streptococcus suis P1/7	38.333	99.338	0.381
comR	Streptococcus suis 05ZYH33	38.333	99.338	0.381