Detailed information NTG0406136

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GO995_RS00685
• Genome accession: NZ_CP046624
• Coordinates: 112685..113599 (+)
• Length: 304 a.a.
• NCBI ID: WP_202913540.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_G3
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 107685..118599

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO995_RS00660 (GO995_00660)	-	108884..109333 (+)	450	WP_157628631.1	DUF523 domain-containing protein	-
GO995_RS00665 (GO995_00665)	purE	109333..109821 (+)	489	WP_074603837.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
GO995_RS00670 (GO995_00670)	purK	109808..110899 (+)	1092	WP_157628632.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
GO995_RS00675 (GO995_00675)	-	110921..111145 (+)	225	WP_157628633.1	phosphoribosylaminoimidazole carboxylase	-
GO995_RS00680 (GO995_00680)	purB	111236..112534 (+)	1299	WP_024344772.1	adenylosuccinate lyase	-
GO995_RS00685 (GO995_00685)	comR	112685..113599 (+)	915	WP_202913540.1	helix-turn-helix domain-containing protein	Regulator
GO995_RS00690 (GO995_00690)	ruvB	113801..114799 (+)	999	WP_074565269.1	Holliday junction branch migration DNA helicase RuvB	-
GO995_RS00695 (GO995_00695)	-	114972..115502 (+)	531	WP_074965577.1	DUF7010 family protein	-
GO995_RS00700 (GO995_00700)	-	115742..116173 (+)	432	WP_074965575.1	low molecular weight protein-tyrosine-phosphatase	-
GO995_RS00705 (GO995_00705)	-	116191..116571 (+)	381	WP_039696049.1	MORN repeat-containing protein	-
GO995_RS00710 (GO995_00710)	-	116568..118361 (+)	1794	WP_157628634.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35892.08 Da
• Isoelectric Point: 4.7669

>NTDB_id=406136 GO995_RS00685 WP_202913540.1 112685..113599(+) (comR) [Streptococcus ruminicola strain CNU_G3]
MEVKKFGNKIRILREKKGISREEFCGDETELSVRQLARIELNQSIPNLSKAQFIANRLGVKLGTLTDGDSLELPKRYKEL
KYLLLRTPTYGDQVRLDRKNDYFDEIAEVFYDVIPEEERLIIDCLQSKFDVHFSDDVNFGDGILNDYFDQVIRKETFNIN
DLILIDLYFACLSSAKKFEGIYGLDFYDDLMKRLVNQKHISPETDLILNNVLLNNIDLAFQFKREYYIERVIVISEKIMT
EIHDFQRRPILSLVEWKYYLKFKHDFALAEQSFTNATLFARLVGDTYLENKLKEEWQLDIDAVE

Nucleotide

• Length: 915 bp

>NTDB_id=406136 GO995_RS00685 WP_202913540.1 112685..113599(+) (comR) [Streptococcus ruminicola strain CNU_G3]
ATGGAAGTGAAAAAATTTGGGAACAAAATTCGTATTTTGCGGGAGAAAAAGGGAATCTCACGCGAAGAATTCTGTGGGGA
CGAGACCGAATTATCCGTACGACAACTAGCACGAATTGAGCTAAATCAATCGATACCTAACCTAAGTAAAGCCCAATTCA
TTGCCAATCGTCTGGGAGTAAAATTAGGTACCTTAACTGATGGTGACAGTTTAGAATTACCAAAGCGGTATAAAGAGCTG
AAGTATTTACTTCTTCGAACACCTACATATGGAGACCAGGTACGACTTGATCGAAAAAATGACTATTTTGATGAGATTGC
TGAAGTATTTTATGATGTTATTCCAGAAGAAGAAAGGTTAATCATAGATTGTTTACAGTCAAAATTTGATGTTCATTTTA
GTGACGACGTAAATTTTGGTGATGGTATTTTAAATGATTATTTTGATCAAGTTATTCGTAAAGAGACTTTTAATATCAAT
GATTTAATTTTGATTGATCTTTACTTTGCTTGTCTTTCTTCTGCTAAGAAGTTTGAAGGAATTTATGGTTTGGATTTTTA
CGACGATTTGATGAAAAGGTTGGTAAATCAGAAGCATATTTCACCTGAGACTGATTTAATTTTAAATAATGTATTGTTAA
ATAATATCGACTTAGCGTTCCAATTTAAACGAGAATATTATATTGAGCGTGTTATTGTAATCAGTGAAAAAATTATGACA
GAGATTCATGATTTTCAACGCCGTCCGATTTTAAGTTTGGTGGAGTGGAAGTATTATTTGAAATTTAAACATGATTTTGC
TTTGGCAGAACAATCATTTACGAATGCAACATTATTTGCACGATTGGTTGGTGATACTTATTTAGAAAATAAACTTAAAG
AAGAATGGCAACTTGATATCGATGCTGTAGAGTAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (74-296)

• Helix-turn-helix (HTH_3) (10-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	94.863	96.053	0.911
comR	Streptococcus mutans UA159	54.027	98.026	0.53
comR	Streptococcus pyogenes MGAS8232	49.351	100	0.5
comR	Streptococcus pyogenes MGAS315	45.695	99.342	0.454
comR	Streptococcus suis D9	37.705	100	0.378
comR	Streptococcus suis P1/7	38.333	98.684	0.378
comR	Streptococcus suis 05ZYH33	38.333	98.684	0.378