Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   GOM46_RS03750 Genome accession   NZ_CP046525
Coordinates   758496..759200 (+) Length   234 a.a.
NCBI ID   WP_235084093.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 753496..764200
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS03735 - 754610..754771 (+) 162 WP_235084090.1 hypothetical protein -
  GOM46_RS03740 (GOM46_03715) - 754821..757100 (-) 2280 WP_235084091.1 Xaa-Pro dipeptidyl-peptidase -
  GOM46_RS03745 (GOM46_03720) mutY 757270..758427 (+) 1158 WP_235084092.1 A/G-specific adenine glycosylase -
  GOM46_RS03750 (GOM46_03725) micA 758496..759200 (+) 705 WP_235084093.1 response regulator YycF Regulator
  GOM46_RS03755 (GOM46_03730) micB 759193..760542 (+) 1350 WP_235084094.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GOM46_RS03760 (GOM46_03735) vicX 760544..761353 (+) 810 WP_006150622.1 MBL fold metallo-hydrolase Regulator
  GOM46_RS03765 (GOM46_03740) - 761390..761737 (-) 348 WP_006150616.1 thiol reductase thioredoxin -
  GOM46_RS03770 (GOM46_03745) - 761846..763564 (-) 1719 WP_006150600.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26980.89 Da        Isoelectric Point: 4.6834

>NTDB_id=405067 GOM46_RS03750 WP_235084093.1 758496..759200(+) (micA) [Streptococcus infantis strain SO]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREAIELFEAEKPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLIAVENQEEDTKLQSLQIGDLEILPDAYVAKKYGEELDLT
HREFELLHHLASHLGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=405067 GOM46_RS03750 WP_235084093.1 758496..759200(+) (micA) [Streptococcus infantis strain SO]
ATGAAAAAAATATTGATTGTTGATGATGAGAAACCAATCTCAGATATCATTAAGTTTAATATGACTAAAGAGGGTTATGA
AGTTGTAACAGCCTTTAATGGACGTGAAGCTATTGAACTGTTCGAAGCTGAAAAACCTGATATTATTATTTTGGACTTGA
TGTTACCAGAAATTGATGGTCTGGAAGTGGCTAAAACGATTCGCAAGACAAGTAGTGTTCCAATTATCATGCTTTCAGCA
AAAGATAGCGAGTTTGATAAGGTTATTGGTCTTGAGCTTGGAGCTGATGATTATGTAACAAAACCATTTTCAAACCGTGA
GCTACAAGCGCGTGTTAAGGCTTTGCTTCGTCGTACTGATTTAATAGCAGTGGAGAACCAAGAAGAAGATACAAAATTAC
AAAGTCTTCAAATTGGAGATTTAGAGATTCTTCCTGATGCTTATGTGGCGAAAAAATATGGTGAAGAATTGGATTTAACT
CATAGAGAGTTTGAGTTATTGCATCACTTAGCTTCTCACCTTGGTCAAGTTATTACCCGTGAACACCTTCTTGAAACTGT
TTGGGGATATGATTATTTCGGTGATGTTCGTACTGTTGATGTTACCATTAGACGTCTACGTGAGAAGATTGAAGACACAC
CAAGCAGACCTGAGTATATCTTGACTCGTCGTGGTGTGGGTTATTACATGAGAAATAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.416

99.573

0.91
  vicR Streptococcus mutans UA159

78.723

100

0.791
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.348

98.291

0.436
  covR Streptococcus salivarius strain HSISS4

44.348

98.291

0.436
  scnR Streptococcus mutans UA159

37.069

99.145

0.368

Multiple sequence alignment