Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   GOM47_RS00220 Genome accession   NZ_CP046524
Coordinates   37777..39126 (+) Length   449 a.a.
NCBI ID   WP_235080699.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 32777..44126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS00180 (GOM47_00175) - 33433..33669 (+) 237 WP_235080692.1 acyl carrier protein -
  GOM47_RS00185 (GOM47_00180) - 34121..34309 (+) 189 WP_235080693.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  GOM47_RS00190 (GOM47_00185) - 34327..34494 (+) 168 WP_173259486.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  GOM47_RS00195 (GOM47_00190) - 34504..34692 (+) 189 WP_235080694.1 hypothetical protein -
  GOM47_RS00200 - 34717..34926 (+) 210 WP_235080695.1 bacteriocin immunity protein -
  GOM47_RS00205 (GOM47_00195) - 35040..35258 (+) 219 WP_235080696.1 hypothetical protein -
  GOM47_RS00210 (GOM47_00200) - 35251..35445 (+) 195 WP_235080697.1 hypothetical protein -
  GOM47_RS00215 (GOM47_00205) comA 35611..37764 (+) 2154 WP_235080698.1 peptide cleavage/export ABC transporter ComA Regulator
  GOM47_RS00220 (GOM47_00210) comB 37777..39126 (+) 1350 WP_235080699.1 competence pheromone export protein ComB Regulator
  GOM47_RS00225 (GOM47_00215) purC 39295..40002 (+) 708 WP_235080700.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  GOM47_RS00230 (GOM47_00220) - 40070..43795 (+) 3726 WP_235080701.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49918.02 Da        Isoelectric Point: 5.8223

>NTDB_id=404960 GOM47_RS00220 WP_235080699.1 37777..39126(+) (comB) [Streptococcus oralis strain SOT]
MKPEFLESAEFYHRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVGNYLEENKL
VKQGDLLVQYQQGAEAIQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQANGLRSNVSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQIAKSAIETGASLASQNLAYSLYQSYKSQREENPQAKAQAVAQVEAQLS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEQ
GNFFKIEAETHLTSEQAEKLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=404960 GOM47_RS00220 WP_235080699.1 37777..39126(+) (comB) [Streptococcus oralis strain SOT]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTACCATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTACTCGTGTTTTTACTGGGATTTGCAGTTTTTGCAGAGAAGGAGATTAGTTTGTCTACCAGAGCGACTGTCG
AACCTAGTCGGATCATTGCCAACATTCAGTCGACTAGTAATCAACGCATTGTGGGCAACTATCTGGAAGAAAACAAACTA
GTCAAGCAAGGGGACCTACTCGTTCAGTACCAGCAAGGGGCAGAGGCTATCCAGGTTGAGGCATATGCCAGTCAATTGGA
GATGCTAAAGGATCAAAAAAAGCAGTTGGGATATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGATATCAGGAGATGTTTAGAGATTATCTCAGCCAAGCGAATGGTCTAAGAAGTAATGTTTCTCAGCAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGTCAAACCCAAGCTGAAATCGGGAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGATAGCTAAGTCAGCTATTGAAACAGGCGCTTCCTTGGCCAGTCAGAATCTGGCCTACTCTCTCT
ACCAGTCCTACAAGTCTCAGAGAGAGGAAAATCCGCAAGCTAAGGCTCAGGCTGTTGCACAGGTTGAAGCACAGCTTTCT
CAGTTAGAATCAAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCCGGAACCCAGCAAGCCTATGCGTCAGGCTTAAG
CAGTCAACTGGAATCACTCAAATCTCAGCACTTAGTCAAAGTTGGCCAGGAATTAACTCTTCTAGATCAGAAAATTTTGG
AGGCGGAATCGGGTAAGAAGGTACAGGGAGGTCTCCTCGACAAGGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTCAATCCTGAGACTAGTGAATCTACGATGGTCGCAGAAGGAACCCTGCTAGCCCAACTCTATCCATCCTTGGAAAAAGA
AGGAAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGACTCTGTCCGTTATACTA
CAACTAATGATGCGAAGAATCAAATTTTCCTGGATTCCACGATTACAAGTATTGATGCGACAGCTACAAAGACTGAACAA
GGAAATTTCTTTAAAATTGAGGCGGAGACCCATCTGACTTCTGAGCAGGCTGAAAAACTTCGCTATGGTTTAGAAGGCCG
CCTGCAGATGATCACGGGAAAGAAAAGCTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

88.393

99.777

0.882
  comB Streptococcus pneumoniae Rx1

86.83

99.777

0.866
  comB Streptococcus pneumoniae D39

86.83

99.777

0.866
  comB Streptococcus pneumoniae R6

86.83

99.777

0.866
  comB Streptococcus mitis NCTC 12261

86.83

99.777

0.866
  comB Streptococcus pneumoniae TIGR4

86.607

99.777

0.864
  comB Streptococcus gordonii str. Challis substr. CH1

55.31

100

0.557

Multiple sequence alignment