Detailed information NTG0404959

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: GOM47_RS00215
• Genome accession: NZ_CP046524
• Coordinates: 35611..37764 (+)
• Length: 717 a.a.
• NCBI ID: WP_235080698.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOT
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 30611..42764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM47_RS00170 (GOM47_00165)	recO	31669..32439 (+)	771	WP_235080690.1	DNA repair protein RecO	-
GOM47_RS00175 (GOM47_00170)	plsX	32436..33428 (+)	993	WP_235080691.1	phosphate acyltransferase PlsX	-
GOM47_RS00180 (GOM47_00175)	-	33433..33669 (+)	237	WP_235080692.1	acyl carrier protein	-
GOM47_RS00185 (GOM47_00180)	-	34121..34309 (+)	189	WP_235080693.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
GOM47_RS00190 (GOM47_00185)	-	34327..34494 (+)	168	WP_173259486.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
GOM47_RS00195 (GOM47_00190)	-	34504..34692 (+)	189	WP_235080694.1	hypothetical protein	-
GOM47_RS00200	-	34717..34926 (+)	210	WP_235080695.1	bacteriocin immunity protein	-
GOM47_RS00205 (GOM47_00195)	-	35040..35258 (+)	219	WP_235080696.1	hypothetical protein	-
GOM47_RS00210 (GOM47_00200)	-	35251..35445 (+)	195	WP_235080697.1	hypothetical protein	-
GOM47_RS00215 (GOM47_00205)	comA	35611..37764 (+)	2154	WP_235080698.1	peptide cleavage/export ABC transporter ComA	Regulator
GOM47_RS00220 (GOM47_00210)	comB	37777..39126 (+)	1350	WP_235080699.1	competence pheromone export protein ComB	Regulator
GOM47_RS00225 (GOM47_00215)	purC	39295..40002 (+)	708	WP_235080700.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80377.70 Da
• Isoelectric Point: 8.4116

>NTDB_id=404959 GOM47_RS00215 WP_235080698.1 35611..37764(+) (comA) [Streptococcus oralis strain SOT]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLARLRELAKTTMDGTTALGLVKVAEELGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKKTIHIADPDPGVKMTKISRERFAQEWTGISLFMAPSPDYKPHKEKKQGLLSFLPI
LFKQRGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLILGQRLSID
VILSYIKHVFHLPMSFYATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVTYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSMM
KGDITFKQVHYKYGYGRDVLSNINLTIPQGSKVSFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQHI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELADIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDKLMALDKTLIFIAHRLTIAERTEKVVVLNQGKIVEEGTHADLLARGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=404959 GOM47_RS00215 WP_235080698.1 35611..37764(+) (comA) [Streptococcus oralis strain SOT]
ATGAAATTTGGGAAAAGACACTATCGCCCTCAGGTGGATCAGATGGATTGCGGCGTGGCTTCCTTGGCTATGGTATTTGG
CTACTACGGTAGTTATTACTCCTTGGCTCGTCTACGAGAGTTGGCCAAGACGACCATGGATGGGACGACTGCTTTGGGTC
TTGTAAAGGTAGCAGAGGAGCTTGGTTTTGAAACGCGGGCTATCAAGGCGGATATGACGCTCTTTGACTTGCCAGATTTG
ACCTTTCCCTTTGTGGCTCATGTGCTCAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACAGGTCAGGATAAGAAGAC
CATCCATATCGCTGATCCAGATCCTGGTGTCAAGATGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAATGGACAGGGA
TCAGTCTCTTTATGGCGCCATCTCCAGACTATAAACCCCATAAGGAGAAAAAACAGGGGCTCCTATCCTTCTTGCCAATC
TTATTCAAACAGCGTGGCTTAATTACCAATATCGTCCTAGCGACACTCTTGGTGACCCTGATTAACATTGTAGGTTCTTA
TTATCTGCAGTCTATCATTGATAGTTACGTGCCAGACCAGATGCGCTCAACGCTGGGCATCATCTCTATTGGGCTGGTCA
TCGTCTATATCCTCCAGCAGATTTTGTCCTACGCGCAGGAATATCTCCTACTAATCCTTGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCTTATATTAAGCATGTTTTTCACCTGCCAATGTCCTTTTACGCGACACGCAGGACAGGGGAAATCGTGTC
TCGTTTTACAGATGCCAATAGTATCATCGATGCGCTGGCGTCGACCATTTTGTCTATCTTTTTGGATGTGTCGACGATTT
TGATTATTTCGCTTGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGCCTGCTTGCACTTCCCATTTATACAGTG
ATTATCTTTGCCTTTATGAAGCCTTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAACGGTATTGAGACCATTAAATCTTTGACTAGTGAAAGTTCACGCTATCAAAAGATTGATAAGGAAT
TTGTGACTTATCTGAAAAAATCCTTTACCTACAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCTCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGATGGGAGCAGTGCTCGTCATGGATGGCAAGATGAGTTTGGGCCAGTTGATTACCTA
TAATACCTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATCAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAACCGTCTGAATGAGGTTTATCTGGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTCGAAGATTTGAGCATGATG
AAGGGAGATATAACCTTTAAGCAAGTCCACTATAAGTATGGCTATGGACGGGACGTCTTGTCGAATATCAATTTGACGAT
TCCGCAAGGCTCTAAGGTGTCTTTTGTGGGGATCTCAGGGTCAGGTAAAACCACCTTGGCCAAGATGATGGTTAACTTTT
ACGACCCAAGTCAGGGGGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGATAAAAAAGCCTTGCGCCAGCATATC
AACTATTTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTGGGAGCTAAGGAGGGGACGAC
ACAGGAAGATATCTTACGAGCAGTTGAATTGGCTGATATTCGGGAGGATATCGAGCGCATGCCACTGAATTATCAGACAG
AATTGACTTCGGATGGAGCAGGTATTTCTGGGGGGCAACGGCAGCGAATCGCTCTGGCGCGTGCTCTCTTGACGGATGCA
CCTGTCTTGATCTTGGATGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTGGATAAACTCATGGCTTT
AGACAAGACCTTGATTTTCATCGCCCACCGCTTGACCATTGCTGAGCGGACAGAGAAGGTTGTTGTCTTGAATCAGGGCA
AGATTGTCGAAGAAGGCACCCATGCAGACTTGCTTGCTCGAGGTGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	94.142	100	0.941
comA	Streptococcus mitis SK321	93.863	100	0.939
comA	Streptococcus pneumoniae Rx1	93.863	100	0.939
comA	Streptococcus pneumoniae D39	93.863	100	0.939
comA	Streptococcus pneumoniae R6	93.863	100	0.939
comA	Streptococcus pneumoniae TIGR4	93.445	100	0.934
comA	Streptococcus gordonii str. Challis substr. CH1	80.893	100	0.809
comA/nlmT	Streptococcus mutans UA159	64.714	100	0.647