Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   GOM48_RS01885 Genome accession   NZ_CP046523
Coordinates   383694..385577 (+) Length   627 a.a.
NCBI ID   WP_235098015.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 378694..390577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS01870 (GOM48_01865) fmt 380700..381635 (+) 936 WP_235098011.1 methionyl-tRNA formyltransferase -
  GOM48_RS01875 (GOM48_01870) rsmB 381628..382941 (+) 1314 WP_235098013.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  GOM48_RS01880 (GOM48_01875) - 382957..383697 (+) 741 WP_084946411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GOM48_RS01885 (GOM48_01880) stkP 383694..385577 (+) 1884 WP_235098015.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GOM48_RS01890 (GOM48_01885) - 385665..386423 (+) 759 WP_000344526.1 threonine/serine exporter family protein -
  GOM48_RS01895 (GOM48_01890) - 386425..386880 (+) 456 WP_131200896.1 threonine/serine exporter family protein -
  GOM48_RS01900 (GOM48_01895) - 386999..388171 (+) 1173 WP_235098711.1 hydroxymethylglutaryl-CoA synthase -
  GOM48_RS01905 (GOM48_01900) - 388171..389445 (+) 1275 WP_235098017.1 hydroxymethylglutaryl-CoA reductase, degradative -
  GOM48_RS01910 (GOM48_01905) - 389481..390446 (-) 966 WP_000225990.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68288.63 Da        Isoelectric Point: 9.3409

>NTDB_id=404907 GOM48_RS01885 WP_235098015.1 383694..385577(+) (stkP) [Streptococcus oralis strain SOD]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHSPLSNEEAVRIMGQILLAMRLAHTRGIIHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPAVP
QALENVVIKATAKKLTDRYQSVSEMYVDLSSCLSHNRRREPKLVFDEASKVDTKTLPKVPQSTLTSIPKAKPQLERPQSK
QQTQQVVAEAPVPKPAKKRKFKARYMILLASALLVAASLIWIFSRTPATIAIPDVSGQTVAEAKETLKKANFEVGEEKTE
ASDTVAEGRVIRTDPEARSGRKEGSKVNLIVSSGKQSFQLSNYVGRKSSDVVAELKEKKVPENLIKIEEEESSESDPGTV
IRQTPAAGSTYDLTKATSIVLTVAKKVTSVSMPSYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTTAGTVVSQDP
KSGEKVDLNKTRVKISIYKPKPLPSSSSSSQHGNSGTDTTPSQSNNQGSNPTTDSSDGGRTSSNERN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=404907 GOM48_RS01885 WP_235098015.1 383694..385577(+) (stkP) [Streptococcus oralis strain SOD]
ATGATCCAGATCGGCAAGATTTTTGCCGGACGATATCGGATTATCAAACAGATTGGTCGAGGAGGCATGGCGGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCGGTTAAGGTCCTGAGGACTAACTATCAGACAGATCCGATTG
CTGTGGCACGTTTTCAACGTGAAGCGAGAGCCATGGCGGATCTGGATCATCCCCATATCGTTCGAATAACAGATATCGGT
GAGGAAGACGGTCAGCAGTATCTAGCTATGGAGTATGTGGCAGGGCTTGACCTCAAACGTTATATCAAAGAACATTCCCC
TCTCTCAAATGAAGAAGCCGTCCGTATTATGGGACAGATTCTCTTGGCCATGCGTCTGGCGCATACGAGAGGGATTATCC
ACCGAGATTTGAAACCTCAAAATATCCTATTGACACCAGATGGAACTGCCAAAGTTACAGACTTTGGGATTGCCGTAGCT
TTTGCAGAGACCAGTCTGACACAGACTAACTCCATGCTCGGTTCAGTCCACTATCTCTCACCTGAGCAGGCGCGTGGTTC
CAAGGCAACTGTGCAGAGTGACATCTATGCTATGGGGATTATTTTCTATGAAATGTTGACTGGACATATTCCTTATGATG
GGGACAGTGCAGTGACTATCGCCCTCCAGCATTTCCAAAAACCACTCCCATCTGTTATTGCTGAGAATCCAGCAGTACCG
CAAGCTTTGGAAAATGTCGTTATCAAGGCAACGGCCAAGAAATTGACAGATCGCTATCAGTCCGTATCAGAAATGTATGT
GGACTTGTCGAGTTGTTTGTCTCACAATCGCAGGAGAGAACCAAAGCTAGTCTTTGATGAGGCAAGCAAGGTTGATACCA
AGACCTTGCCTAAAGTTCCACAAAGCACTCTGACCTCTATTCCGAAGGCTAAGCCACAATTAGAGCGACCTCAATCAAAA
CAGCAGACTCAGCAGGTGGTAGCTGAAGCACCAGTACCAAAACCAGCGAAAAAACGGAAGTTTAAAGCTCGCTATATGAT
TTTACTGGCCAGTGCCTTGCTAGTTGCAGCCTCTTTGATTTGGATCTTCTCCCGAACTCCAGCGACTATTGCTATTCCAG
ATGTATCGGGACAGACAGTTGCTGAAGCTAAAGAAACACTGAAGAAAGCTAATTTTGAAGTAGGTGAAGAAAAGACCGAG
GCCAGCGACACAGTAGCCGAAGGTCGCGTCATTCGAACAGATCCAGAAGCTAGAAGCGGTCGAAAAGAAGGAAGCAAAGT
AAATCTAATCGTTTCATCAGGTAAGCAATCCTTCCAACTAAGTAACTATGTAGGACGTAAGTCCTCGGATGTTGTCGCAG
AGCTCAAAGAGAAAAAGGTTCCAGAAAATCTTATCAAGATCGAGGAAGAGGAATCTAGCGAAAGCGATCCAGGAACAGTC
ATTAGGCAAACCCCAGCTGCAGGAAGCACTTACGACCTAACAAAGGCAACAAGTATTGTATTGACAGTTGCTAAGAAGGT
GACCAGCGTTTCGATGCCAAGTTACATTGGTTCAAGTCTTGAATTTACTAAGAACAATTTGACTCAGATTGTTGGTGTAA
AAGAGGCCAATATCGAAGTTGTGGAAGTATCAACTGCTCCTGAAGGAACTACTGCAGGAACAGTTGTTAGTCAGGACCCT
AAATCTGGAGAAAAGGTAGATCTCAATAAAACACGTGTTAAGATTTCTATTTATAAACCAAAACCACTTCCTTCTTCATC
AAGTTCGTCTCAACACGGAAATTCAGGAACAGACACGACGCCTTCACAGAGTAACAATCAAGGTAGCAACCCTACAACGG
ATTCTTCAGATGGCGGTAGAACGTCAAGCAATGAACGAAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

77.53

92.982

0.721
  stkP Streptococcus pneumoniae D39

77.187

92.982

0.718
  stkP Streptococcus pneumoniae R6

77.187

92.982

0.718
  stkP Streptococcus pneumoniae Rx1

77.015

92.982

0.716
  pknB Streptococcus mutans UA159

56.401

92.185

0.52
  stkP/pknB Streptococcus salivarius strain HSISS4

51.952

93.939

0.488

Multiple sequence alignment