Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   GOM48_RS00230 Genome accession   NZ_CP046523
Coordinates   38408..39757 (+) Length   449 a.a.
NCBI ID   WP_235097638.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 33408..44757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS00185 (GOM48_00180) - 33947..34090 (+) 144 WP_235097625.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  GOM48_RS00190 (GOM48_00185) - 34106..34264 (+) 159 WP_235097627.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  GOM48_RS00195 - 34278..34454 (+) 177 WP_235097628.1 hypothetical protein -
  GOM48_RS00200 - 34648..34803 (+) 156 WP_000732133.1 hypothetical protein -
  GOM48_RS00205 (GOM48_00190) - 34842..35054 (+) 213 WP_235097630.1 bacteriocin immunity protein -
  GOM48_RS00210 (GOM48_00195) - 35135..35323 (+) 189 WP_131200675.1 hypothetical protein -
  GOM48_RS00215 (GOM48_00200) - 35348..35557 (+) 210 WP_235097632.1 bacteriocin immunity protein -
  GOM48_RS00220 - 35882..36076 (+) 195 WP_235097634.1 hypothetical protein -
  GOM48_RS00225 (GOM48_00205) comA 36242..38395 (+) 2154 WP_235097636.1 peptide cleavage/export ABC transporter ComA Regulator
  GOM48_RS00230 (GOM48_00210) comB 38408..39757 (+) 1350 WP_235097638.1 competence pheromone export protein ComB Regulator
  GOM48_RS00235 (GOM48_00215) purC 39925..40632 (+) 708 WP_000038498.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  GOM48_RS00240 (GOM48_00220) - 40670..44395 (+) 3726 WP_235097640.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50018.01 Da        Isoelectric Point: 5.0575

>NTDB_id=404886 GOM48_RS00230 WP_235097638.1 38408..39757(+) (comB) [Streptococcus oralis strain SOD]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLMFLLGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGELLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ANISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQAGEDPQAKSQVIAQVDAQIS
QLESSLATYRVQYAGSGAQQAYASGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPALEREGKTKLTAYLSSKDVARLKVGDSVRFTTTKDANKELILVSAITNIDATATKTEK
GNFFKIEAETSLTPEQAEELRYGSEGRLTLITGKKSYFRYYWDQFLNRE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=404886 GOM48_RS00230 WP_235097638.1 38408..39757(+) (comB) [Streptococcus oralis strain SOD]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGCTCATGTTTTTACTGGGATTTGCAGTTTTTGCAGAGAAAGAGATTAGTTTGTCTACCAGAGCGACAGTCG
AACCTAGTCGGATTATTGCCAATATCCAGTCGACTAGCAATCAACGCATCGTGGCCAATTATCTGGAAGAAAACAAGTTG
GTCAAGCAGGGGGAACTACTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTAGAGGCATATGCCAGTCAATTGGA
GATGCTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGCGATCAATTTCCAGAGGCGG
ATAAGTTTGGTTATCAGGAGATGTTTAGAGACTATCTCAGCCAAGCTAGTAGTCTTAGGAGCAATGTTTCGCAGCAAAAT
GCCAACATCTCCTCGCAGAATGCGGCAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGCCAAACAGAGGATAA
AATCCGAGACTACAAAACAGCTAAGTCGGCGATTGAAAAGGGAGATCAACTAGATAGTCAGAATCCAGCCTACTCTTTCT
ATCAGACCTATAAAAACCAAGCTGGAGAAGATCCGCAAGCTAAATCACAAGTTATTGCACAGGTGGATGCCCAAATTAGC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTACAGTATGCGGGATCTGGAGCTCAACAAGCCTACGCAAGTGGACTGGA
TAGTCAGCTTGAATCCCTTAAGTCCCAGCACCTAGTCAAAGTCGGTCAGGAATTAACCCTTTTGGATCAGAAAATTTTAG
AAGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGACAAGGGGAAAATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAAACCAGTGATTCTACGATGGTTGCAGAAGGGACCCTGCTAGCCCAACTGTACCCGGCCTTGGAAAGAGA
AGGCAAAACCAAACTCACAGCTTATCTCAGTTCGAAAGATGTTGCAAGACTCAAAGTAGGTGATTCTGTTCGCTTTACTA
CAACCAAGGATGCCAACAAAGAACTTATTCTTGTTTCTGCGATTACGAATATTGATGCGACAGCTACCAAGACTGAAAAG
GGAAATTTCTTTAAAATAGAGGCGGAGACAAGTCTGACTCCTGAACAAGCAGAAGAGCTTCGCTACGGTTCAGAAGGACG
TTTGACACTAATCACAGGAAAGAAAAGTTATTTCCGCTATTATTGGGATCAATTTTTAAACAGAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

81.514

100

0.815
  comB Streptococcus pneumoniae Rx1

81.292

100

0.813
  comB Streptococcus pneumoniae D39

81.292

100

0.813
  comB Streptococcus pneumoniae R6

81.292

100

0.813
  comB Streptococcus pneumoniae TIGR4

80.846

100

0.808
  comB Streptococcus mitis NCTC 12261

79.955

100

0.8
  comB Streptococcus gordonii str. Challis substr. CH1

56.222

100

0.563

Multiple sequence alignment