Detailed information NTG0404880

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GE024_RS10750
• Genome accession: NZ_CP046521
• Coordinates: 2175918..2177141 (+)
• Length: 407 a.a.
• NCBI ID: WP_093999374.1
• Uniprot ID: A0A3P5XRA7
• Organism: Streptococcus canis strain HL_100
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2170918..2182141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE024_RS10720 (GE024_10800)	recF	2171362..2172465 (-)	1104	WP_093999512.1	DNA replication/repair protein RecF	-
GE024_RS10725 (GE024_10805)	yaaA	2172467..2172880 (-)	414	WP_093999511.1	S4 domain-containing protein YaaA	-
GE024_RS10730 (GE024_10810)	-	2172960..2173859 (-)	900	Protein_2068	IS30 family transposase	-
GE024_RS10735 (GE024_10815)	-	2174082..2174906 (-)	825	Protein_2069	DDE-type integrase/transposase/recombinase	-
GE024_RS10745 (GE024_10825)	rlmH	2175226..2175705 (-)	480	WP_093999375.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GE024_RS10750 (GE024_10830)	htrA	2175918..2177141 (+)	1224	WP_093999374.1	S1C family serine protease	Regulator
GE024_RS10755 (GE024_10835)	spo0J	2177238..2178005 (+)	768	WP_093999373.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42616.03 Da
• Isoelectric Point: 5.7603

>NTDB_id=404880 GE024_RS10750 WP_093999374.1 2175918..2177141(+) (htrA) [Streptococcus canis strain HL_100]
MPTMKHILKFLGITLIGFLGGILAIVTVNNTSQQSSSTSHSGSATTSKMVFNNTTDTTKAVNVIQNAVVSVINYQDDPSS
SLSNPYIKLFGEDQAKENKDAELTIFSEGSGVIYRKDGNSAYVVTNNHVIDGAKRIEILMADGSKVVGELVGADTYSDLA
VVKISSDKIKTIAEFADSSKLNVGEVAIAIGSPLGTQYANSVTEGIVSSLSRTVTLKNENGETVSTNAIQTDAAINPGNS
GGPLINIEGQVIGINSSKISSTPTGNNGNSGAVEGIGFAIPSSDVIKIIKQLETNGEVIRPALGISMVNLNDLSTNALRQ
INIPTSVTGGIVVASVQAGMPATGKLTQYDVITEIDGKAVNSISDLQSNLYGHNINDTIKVTFYRGTAKKKADIKLTKTT
QDLSKAQ

Nucleotide

• Length: 1224 bp

>NTDB_id=404880 GE024_RS10750 WP_093999374.1 2175918..2177141(+) (htrA) [Streptococcus canis strain HL_100]
ATGCCCACTATGAAACATATCTTAAAATTCTTAGGTATTACACTCATCGGATTTTTAGGAGGAATCTTGGCTATTGTTAC
AGTTAATAATACTAGTCAACAATCTTCTTCTACGTCACACTCAGGTAGTGCAACAACCAGTAAAATGGTTTTCAATAATA
CCACTGATACTACAAAAGCTGTTAACGTTATTCAAAATGCAGTGGTATCCGTTATTAATTATCAAGATGATCCTTCTTCA
TCTTTGTCTAATCCTTACATAAAACTTTTTGGAGAGGATCAGGCAAAAGAAAATAAGGATGCTGAACTAACAATTTTTAG
CGAAGGTTCTGGTGTCATTTATCGAAAAGACGGTAATTCTGCCTATGTTGTTACTAATAATCACGTTATTGATGGTGCTA
AGCGCATTGAAATCCTTATGGCTGATGGATCTAAAGTGGTTGGGGAATTAGTCGGCGCTGATACCTATTCTGACTTAGCA
GTTGTCAAAATTTCTTCTGATAAGATTAAAACAATCGCGGAATTTGCTGATTCAAGCAAACTTAATGTTGGAGAAGTAGC
TATTGCTATAGGTAGTCCTTTAGGAACTCAATATGCCAATTCTGTCACCGAAGGGATTGTTTCAAGTCTCAGTCGTACTG
TTACCTTAAAAAATGAAAATGGTGAAACTGTTTCAACCAATGCTATTCAAACAGACGCTGCCATTAATCCAGGAAACTCT
GGTGGTCCACTCATTAATATCGAAGGACAAGTCATCGGAATTAATTCAAGTAAAATTTCCTCTACACCAACTGGTAATAA
TGGTAATAGCGGAGCTGTCGAAGGAATCGGCTTTGCTATTCCATCTAGTGATGTTATCAAAATTATCAAGCAATTAGAAA
CCAATGGAGAAGTCATCAGACCTGCCCTTGGTATCTCTATGGTTAACTTAAATGATTTATCAACCAATGCCCTTCGTCAA
ATCAATATTCCAACTAGTGTGACAGGTGGGATTGTAGTCGCTTCTGTTCAAGCTGGCATGCCAGCTACAGGTAAACTTAC
TCAGTACGATGTGATTACCGAAATCGATGGTAAAGCCGTCAACTCAATTAGTGATCTTCAAAGTAATTTATATGGACATA
ACATTAATGATACTATCAAAGTAACCTTTTACAGAGGGACAGCAAAGAAAAAAGCAGACATCAAATTAACGAAGACTACA
CAAGATTTAAGTAAAGCGCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (109-254)

• PDZ domain (PDZ_2) (301-396)

3D structure

• AlphaFold DB: A0A3P5XRA7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.794	99.017	0.602
htrA	Streptococcus mitis NCTC 12261	54.3	100	0.543
htrA	Streptococcus pneumoniae Rx1	54.3	100	0.543
htrA	Streptococcus pneumoniae D39	54.3	100	0.543
htrA	Streptococcus pneumoniae R6	54.3	100	0.543
htrA	Streptococcus pneumoniae TIGR4	54.3	100	0.543
htrA	Streptococcus gordonii str. Challis substr. CH1	54.975	98.771	0.543