Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MARKY_RS02840 Genome accession   NC_015387
Coordinates   529299..530315 (-) Length   338 a.a.
NCBI ID   WP_041657787.1    Uniprot ID   -
Organism   Marinithermus hydrothermalis DSM 14884     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 524299..535315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MARKY_RS02815 (Marky_0551) - 524565..525026 (-) 462 WP_052297147.1 hypothetical protein -
  MARKY_RS02820 (Marky_0552) - 525214..526503 (-) 1290 WP_013703355.1 HAMP domain-containing sensor histidine kinase -
  MARKY_RS02825 (Marky_0553) - 526507..527163 (-) 657 WP_013703356.1 response regulator transcription factor -
  MARKY_RS02830 (Marky_0554) dusA 527231..528250 (-) 1020 WP_013703357.1 tRNA dihydrouridine(20/20a) synthase DusA -
  MARKY_RS02835 (Marky_0555) ispH 528261..529265 (-) 1005 WP_041657786.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
  MARKY_RS02840 (Marky_0556) dprA 529299..530315 (-) 1017 WP_041657787.1 DNA-processing protein DprA Machinery gene
  MARKY_RS02845 (Marky_0557) era 530392..531291 (+) 900 WP_013703360.1 GTPase Era -
  MARKY_RS02850 (Marky_0558) - 531367..532248 (+) 882 WP_013703361.1 acyltransferase -
  MARKY_RS02855 (Marky_0559) - 532203..532607 (-) 405 WP_013703362.1 HEPN domain-containing protein -
  MARKY_RS02860 (Marky_0560) - 532612..532953 (-) 342 WP_013703363.1 DUF427 domain-containing protein -
  MARKY_RS02865 (Marky_0561) purF 533012..534439 (-) 1428 WP_245526785.1 amidophosphoribosyltransferase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 35214.40 Da        Isoelectric Point: 5.5208

>NTDB_id=40317 MARKY_RS02840 WP_041657787.1 529299..530315(-) (dprA) [Marinithermus hydrothermalis DSM 14884]
MDWLSLALTPGVGPARFMRAFQEGAASPERVRAVLGPRIAAAYAETLADGVAERARAQAAAHGARILGLWEADYPEALRH
LTDPPLVLYVRGALPPYEQSVAIVGTRRASPWAKAWTRRTARALAEAGVAVISGLARGIDTEAHAGALEGGGLTVGVLGS
GLDRIYPRENQALAERVTLVSELPFGEPPRPEYFPRRNRVVAALARAVLVVEAPPKSGALITAALALELGREVLAVPGRP
TDPGAAGPNRLIQEGAGLVTNAAEVLEALNLAPTPALRPELTEAEARLYAALRAAGEALPDELAEELQLTAGEVLAGLAA
LELKGLAQALPGGRYAAV

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=40317 MARKY_RS02840 WP_041657787.1 529299..530315(-) (dprA) [Marinithermus hydrothermalis DSM 14884]
GTGGACTGGCTCTCCCTGGCCTTAACCCCTGGCGTTGGCCCGGCGCGGTTCATGCGGGCTTTTCAGGAGGGGGCGGCCTC
CCCGGAGCGCGTCCGGGCGGTGCTGGGCCCCCGGATCGCCGCGGCGTACGCCGAAACCCTGGCCGACGGCGTCGCCGAGC
GCGCTCGAGCCCAGGCGGCAGCCCACGGCGCGCGGATCCTGGGGTTGTGGGAGGCGGACTACCCCGAGGCGCTGCGCCAC
CTTACGGACCCGCCGCTCGTGCTGTACGTGCGGGGGGCGTTGCCCCCCTACGAGCAAAGCGTCGCGATCGTGGGAACCCG
CCGAGCCTCCCCCTGGGCCAAGGCCTGGACGCGCCGAACCGCCCGCGCCCTGGCCGAGGCCGGCGTGGCGGTCATCTCCG
GCCTCGCGCGCGGCATCGACACCGAAGCCCACGCGGGGGCCCTCGAGGGCGGCGGACTCACCGTGGGGGTCCTGGGCAGC
GGGCTGGACCGCATCTACCCCCGGGAGAACCAGGCGCTCGCCGAGCGCGTCACGCTCGTGAGCGAGCTGCCCTTCGGCGA
ACCCCCCCGGCCCGAGTACTTCCCCCGTCGTAACCGCGTGGTCGCCGCCCTGGCCCGGGCCGTGCTCGTGGTGGAGGCTC
CTCCAAAGTCCGGGGCGCTCATCACCGCCGCGCTGGCCCTCGAGCTCGGCCGGGAGGTGCTCGCCGTGCCCGGCCGCCCC
ACCGACCCCGGCGCGGCCGGCCCCAACCGGCTGATCCAGGAAGGCGCGGGGCTCGTCACGAACGCGGCAGAGGTCCTCGA
AGCCCTGAACCTCGCTCCAACCCCCGCGCTCCGGCCCGAGCTTACCGAGGCGGAGGCCCGGCTGTACGCGGCACTGCGCG
CGGCGGGCGAAGCCCTACCGGACGAGCTGGCGGAAGAGCTACAGCTCACGGCCGGCGAGGTGCTCGCGGGCCTCGCGGCC
CTCGAGCTCAAGGGCCTCGCCCAGGCGCTGCCGGGCGGGCGGTACGCCGCCGTGTAG

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(272-333)

DNA recombination-mediator protein A (DNA_processg_A)

(61-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Thermus thermophilus HB27

55.655

99.408

0.553
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

46.742

100

0.488
  dprA Neisseria gonorrhoeae strain FA1090

38.86

100

0.444
  dprA Neisseria gonorrhoeae MS11

38.601

100

0.441
  dprA Vibrio campbellii strain DS40M4

38.764

100

0.408
  dprA Vibrio cholerae strain A1552

37.047

100

0.393
  dprA Neisseria meningitidis strain C311

43.11

83.728

0.361
  dprA Neisseria meningitidis MC58

43.11

83.728

0.361

Multiple sequence alignment