Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   GL183_RS05250 Genome accession   NZ_CP046355
Coordinates   984712..985521 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain 475     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 979712..990521
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL183_RS11645 - 981212..981337 (-) 126 WP_001818232.1 hypothetical protein -
  GL183_RS05235 (GL183_05275) mutY 981434..982609 (+) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  GL183_RS05240 (GL183_05280) micA 982664..983368 (+) 705 WP_000722076.1 response regulator YycF Regulator
  GL183_RS05245 (GL183_05285) micB 983361..984710 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GL183_RS05250 (GL183_05290) vicX 984712..985521 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  GL183_RS05255 (GL183_05295) - 985612..985854 (+) 243 WP_024477795.1 DUF6290 family protein -
  GL183_RS05260 (GL183_05300) - 985856..986110 (+) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  GL183_RS05265 (GL183_05305) - 986185..988056 (+) 1872 WP_000150986.1 Eco57I restriction-modification methylase domain-containing protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=403047 GL183_RS05250 WP_001289493.1 984712..985521(+) (vicX) [Streptococcus pneumoniae strain 475]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=403047 GL183_RS05250 WP_001289493.1 984712..985521(+) (vicX) [Streptococcus pneumoniae strain 475]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTCTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment